基于LASSO回归的A型主动脉夹层患者行孙氏手术后住院时长影响因素分析  

Analysis of factors affecting length of hospital stay after Sun′s procedure in patients with type A aortic coarctation based on LASSO regression

作　　者：张红良[1] 粟昭隐 柴翠翠 林婧[1] 刘春霞[1] ZHANG Hongliang;SU Zhaoyin;CHAI Cuicui;LIN Jing;LIU Chunxia(Department of Blood Transfusion,the First Hospital of Lanzhou University,Lanzhou 730000,China;First Clinical Medical College of Lanzhou University)

机构地区：[1]兰州大学第一医院输血科,甘肃兰州730000 [2]兰州大学第一临床医学院

出　　处：《中国输血杂志》2023年第9期795-798,共4页Chinese Journal of Blood Transfusion

基　　金：兰州大学学生创新创业行动计划(20220060178)。

摘　　要：目的探讨A型主动脉夹层患者行孙氏手术后住院时长的影响因素。方法收集2018年1月—2023年6月兰州大学第一医院行A型主动脉夹层孙氏手术患者的临床资料、相关实验室指标及围术期输血情况,通过LASSO回归筛选与患者住院时长相关的特征,通过线性回归分析确定患者住院时长延长的风险因素。结果对242名患者的统计分析显示红细胞输注量、血浆输注量、血小板输注量、自体回收血量是A型主动脉夹层患者术后住院时长的影响因素,对住院总时长y拟合的线性回归方程的总离均差平方和差异有统计学意义(F=10.504,P<0.001)。结论围术期红细胞输注量、血浆输注量、血小板输注量及自体回收血量是A型主动脉夹层行孙氏手术患者术后住院时长延长的风险因素,减少术中失血量可能有助于预防患者住院时间过长及其他不良情况。Objective To investigate the factors affecting the length of hospitalization after the Sun’s procedure in pa⁃tients with type A aortic coarctation.Methods From January 2018 to June 2023,the clinical data,related laboratory indi⁃cators and perioperative blood transfusion data of patients with type A aortic dissection who underwent Sun′s procedure in the First Hospital of Lanzhou University were collected.LASSO regression was used to screen the characteristics related to the length of hospital stay,and linear regression analysis was used to determine the risk factors for prolonged length of hospital stay.Results The statistical analysis of 242 patients showed that the amount of red blood cell transfusion,plasma transfu⁃sion,platelet transfusion and autologous blood transfusion were the influencing factors of the length of hospital stay in patients with type A aortic dissection after operation.The total sum of squared deviations of the linear regression equation fitting the total length of hospital stay was statistically significant(F=10.504,P<0.001).Conclusion Perioperative red blood cell transfusion,plasma transfusion,platelet transfusion and autologous blood transfusion are risk factors for prolonged postoperative hospitalization in patients undergoing the Sun's procedure for type A aortic coarctation.Control of operation time and reduction of intraoperative blood loss may help to prevent prolonged postoperative hospital stay and other adverse conditions.

关 键 词：A型主动脉夹层 术后 住院时长 影响因素 

分 类 号：R457.1[医药卫生—治疗学] R543.1[医药卫生—临床医学]