多模态超声评价成人卵圆孔未闭的临床应用价值  

Clinical application value of multi-modal ultrasound in evaluating patent foramen ovale of adult patients

作　　者：王戏丹[1] 杨道玲[1] 陈静婉[1] 吴玉莲 WANG Xidan;YANG Daoling;CHEN Jingwan;WU Yulian(Department of Ultrasound,Jinhua Central Hospital,Jinhua 321000,Zhejiang,China)

机构地区：[1]金华市中心医院超声医学科,浙江金华321000

出　　处：《中国现代医生》2023年第27期37-40,共4页China Modern Doctor

基　　金：浙江省医药卫生科技计划项目(2020KY1012);金华市科技计划重点项目(2022-3-083)。

摘　　要：目的探讨多模态超声评价成人卵圆孔未闭(patent foramen ovale,PFO)的临床应用价值。方法回顾性收集金华市中心医院122例经多模态超声诊断为PFO的患者,所有患者均行经胸超声心动图右心声学造影(contrast-transthoracic echocardiography,cTTE)和经食道超声心动图右心声学造影(contrast-transesophageal echocardiography,cTEE)检查。按有无临床症状分为病例组(65例)和无症状对照组(57例),比较两组患者的PFO参数差异。结果两组患者的PFO形态学参数比较:病例组PFO最大开放直径≥2mm的发生率、PFO合并房间隔膨出瘤(atrial septal aneurysm,ASA)的发生率均高于无症状对照组(53.8%vs.29.8%,10.8%vs 1.8%,P<0.05);两组患者长隧道PFO的发生率比较差异无统计学意义(52.3%vs.47.4%,P>0.05)。两组患者的PFO功能学参数比较:病例组PFO中至大量右向左分流(right-to-left shunt,RLS)的发生率高于无症状对照组(78.5%vs.50.9%,P<0.05)。结论多模态超声可准确评价PFO的形态学和功能学特征,具有重要的临床应用价值,可为PFO的个体化诊治提供可靠的影像学依据。Objective To investigate the clinical application value of multi-modal ultrasound in evaluating patent foramen ovale(PFO)of adult patients.Methods A retrospective analysis was performed on 122 patients diagnosed as PFO by multi-modal ultrasound,including 65 patients in the symptomatic group and 57 patients in the asymptomatic control group.All patients underwent contrast-transthoracic echocardiography(cTTE)and contrast-transesophageal echocardiography(cTEE).The difference of PFO between the two groups were analyzed.Results Comparison of morphological parameters between the two groups showed that the incidence of large PFO(maximum open diameter≥2mm)and frequency of atrial septal aneurysm(ASA)were higher in the symptomatic group than that in the asymptomatic control group(53.8%vs.29.8%,10.8%vs.1.8%,P<0.05);No statistical difference was found in the incidence of long PFO tunnel between the two groups(52.3%vs.47.4%,P>0.05).Comparison of PFO functional parameters between two groups of patients:The incidence of right-to-left shunt(RLS)in the case group was higher than that in the asymptomatic control group(78.5%vs.50.9%,P<0.05).Conclusion Multi-modal ultrasound can accurately evaluate the morphological and functional characteristics of PFO,and provide a reliable imaging basis for diagnosis and treatment of patients with PFO.

关 键 词：卵圆孔未闭 经食道超声心动图 右心声学造影 多模态超声 

分 类 号：R445[医药卫生—影像医学与核医学]