虚拟模板表面分子印迹聚合物固相萃取噻虫嗪  

Virtual Template-based Surface Molecularly Imprinted Polymers for Solid-phase Extraction of Thiamethoxam

作　　者：杜雪 孙梦圆 翁娇静 田园[1] 陈静[1] 何娟[1] 李华雨 DU Xue;SUN Meng-yuan;WENG Jiao-jing;TIAN Yuan;CHEN Jing;HE Juan;LI Hua-yu(School of Chemistry and Chemical Engineering,Henan University of Technology,Zhengzhou 450001,China;Technology Center,Henan Cigarette Industrial Reconstituted Tobacco Sheet,Xuchang 461100,China)

机构地区：[1]河南工业大学化学化工学院,河南郑州450001 [2]河南卷烟工业烟草薄片有限公司技术中心,河南许昌461100

出　　处：《化学试剂》2023年第10期110-116,共7页Chemical Reagents

基　　金：国家自然科学基金项目(22279029)。

摘　　要：采用共价有机骨架MCTP-1为载体材料,6-苄氨基嘌呤为虚拟模板,采用沉淀聚合的方法合成噻虫嗪表面分子印迹聚合物(MCTP-1@MIPs)。利用红外光谱、扫描电镜和X-射线衍射对所合成的聚合物进行表征。吸附测试表明,在0.5~30μg/mL测定范围内最大吸附量可达8.81μg/mg,且10 min即可达吸附-解析平衡,聚合物对噻虫嗪的印迹因子为2.04,对于噻虫嗪具有高选择性。将聚合物作为柱填料,制备成固相萃取柱,优化固相萃取柱使用条件,使用高效液相色谱-二极管阵列检测器进行检测,建立一种灵敏可靠的检测噻虫嗪的方法。为水中噻虫嗪残留的分离富集检测提供了新思路。A novel surface molecularly imprinted polymers(MCTP-1@MIPs)was synthesized through precipitation polymerization using a covalent organic framework MCTP-1 as the carrier material and 6-benzylaminopurine as a virtual template.The synthesized polymers were characterized using Fourier-transform infrared spectroscopy,scanning electron microscopy,and X-ray diffraction.Adsorption tests revealed a maximum adsorption capacity of 8.81μg/mg within the concentration range of 0.5~30μg/mL.Furthermore,adsorption-desorption equilibrium was achieved within 10 min.The polymers exhibited high selectivity for thiamethoxam,with an imprinting factor of 2.04.The polymers were further employed as column packing materials to prepare solid-phase extraction columns.Conditions for the solid-phase extraction columns were optimized,and a sensitive and reliable method for detecting new neonicotinoid pesticides was established using high-performance liquid chromatography coupled with a diode array detector.This research offers a novel perspective for the separation,enrichment,and detection of neonicotinoid pesticides in water,presenting innovative ideas for the analysis and monitoring of these compounds.

关 键 词：表面分子印迹聚合物 噻虫嗪 共价有机骨架 固相萃取 分离介质 

分 类 号：O652.62[理学—分析化学]