Ⅰ群禽腺病毒的分离检测方法与疫苗研究进展  

Development of Isolation,Identification and Vaccine for GroupⅠAvian Adenovirus

作　　者：龙海川 张鹤平 苗立中[2,3] 张文通 于新友 徐新蕊 LONG Haichuan;ZHANG Heping;MIAO Lizhong;ZHANG Wentong;YU Xinyou;XU Xinrui(College of Life Science and Food Engineering,Hebei University of Engineering,Handan,Hebei 056038;Shandong Binzhou Animal Science&Veterinary Medicine Academy,Binzhou,Shandong 256600;Shandong Lvdu Bio-science&Technology Co.,Ltd.,Binzhou,Shandong 256600)

机构地区：[1]河北工程大学生命科学与食品工程学院,河北邯郸056038 [2]山东省滨州畜牧兽医研究院,山东滨州256600 [3]山东绿都生物科技有限公司,山东滨州256600

出　　处：《中国家禽》2023年第10期76-83,共8页China Poultry

基　　金：山东省家禽产业技术体系计划资助项目(SDAIT-11-16);滨州市农社领域科技创新政策引导计划项目(2022KTPY003)。

摘　　要：Ⅰ群禽腺病毒感染主要引起禽包涵体肝炎、心包积液综合征等,具有传播速度快、传播范围广的特点,给我国禽养殖业带来了严重的经济损失。Ⅰ群禽腺病毒分为12种血清型,各血清型之间不仅能交叉感染,还能与其他禽类致病微生物发生混合感染而且各个血清型之间交叉保护很弱甚至没有,给Ⅰ群禽腺病毒病诊断和疫苗研发带来很多困难。文章对Ⅰ群禽腺病毒的分离鉴定、实验室检测以及疫苗研发最新进展进行综述,为Ⅰ群禽腺病毒检测方法和疫苗研发提出提供合理的建议。GroupⅠavian adenovirus infection mainly causes avian inclusion body hepatitis,pericardial effusion syndrome,which leads to severe economic losses to poultry industry in China with the characteristics of rapid transmission rate and wide spread.Due to 12 serotypes,groupⅠavian adenovirus can not only cross infection,but also cause mixed infection with other avi⁃an pathogenic microorganisms,and there is weak or even no cross protection among 12 serotypes,which results in many difficul⁃ties in groupⅠavian adenovirus diagnosis and vaccine development.In this review,the isolation and identification methods,lab⁃oratory tests,and recent advances in vaccine development for groupⅠavian adenoviruse were summarized,which would give rea⁃sonable suggestions for detection and vaccine development of groupⅠavian adenovirus.

关 键 词：禽腺病毒 检测 疫苗 

分 类 号：S855.3[农业科学—临床兽医学]