福建泉州石香薷萃取物的GC-MS分析  

GC-MS Analysis of Extracts From Mosla chinensis Maxim.in Quanzhou of Fujian Province

作　　者：杨晓烨 李赞锦 张鸿燕 赖晨楠 苟文韬 洪铃冰 叶明星 郭琳娟 张伟云 YANG Xiaoye;LI Zanjing;ZHANG Hongyan;LAI Chennan;GOU Wentao;HONG Lingbing;YE Mingxing;GUO Linjuan;ZHANG Weiyun(Department of Pharmacy,Xiamen Medical College/Xiamen Key Laboratory of Traditional Chinese Medicine Bioengineering,Xiamen 361023,China;College of Pharmacy,Fujian Medical University,Fuzhou 350122,China)

机构地区：[1]厦门医学院药学系/厦门市中药生物工程重点实验室,福建厦门361023 [2]福建医科大学药学院,福建福州350122

出　　处：《中国民族民间医药》2023年第18期33-39,共7页Chinese Journal of Ethnomedicine and Ethnopharmacy

基　　金：厦门医学院大学生创新创业项目(X202212631025,X202212631016);厦门医学院校级一流课程项目(XBJK2021027);厦门医学院教育教学改革研究项目-金课建设培育计划(XBJK2019013)。

摘　　要：目的:研究分析福建泉州产石香薷(Mosla chinensis Maxim.)超临界萃取物的化学成分。方法:采用超临界流体萃取法(supercritical fluid extraction,SFE)得到石香薷萃取物;使用薄层色谱法(thin-layer chromatography,TLC)进行成分预试和气相色谱-质谱联用仪(gas chromatography-mass spectrometry,GC-MS)进行成分分析。结果:石香薷萃取物经TLC推测,可能含有酸性、醛类、酮类和油脂类化合物,通过GC-MS分析,提示可能含有112个化合物,其中相对含量最高的是百里香酚(C_(10)H_(14)O),为66.23%。结论:经过TLC和GC-MS分析,初步确定了福建泉州产石香薷超临界萃取物化学成分的种类和相对含量,为研究石香薷化学成分的药理作用打下坚实的基础,也为福建泉州产石香薷的开发利用提供文献参考。Objective To study the chemical composition of the extracts of Mosla chinensis Maxim.in Quanzhou of Fujian Province.Methods Supercritical Fluid Extraction(SFE)was used for extraction,The components of Mosla chinensis Maxim.were pretested by TLC,itschemical compositions were preliminarily identified by Gas Chromatography-Mass Spectrometry(GC-MS).Results The components of Mosla chinensis Maxim.were speculated by TLC,which may contain acidic compounds,aldehydes,ketones and oil compounds,112 compounds may becontained by GC-MS analysis,among which the highest relative content was thymol(C_(10)H_(14)O),accounting for 66.23%.Conclusion The types and relative contents of chemical components of supercritical extracts of Mosla chinensis Maxim.in Quanzhou,Fujian Province were preliminarily identified by TLC and GC-MS,which can lay a solid foundation for future research on the pharmacological effects of the chemical components of Mosla chinensis Maxim.and provide literature references for the future development and utilization of Mosla chinensis Maxim.

关 键 词：石香薷 超临界流体萃取法 TLC GC-MS 化学成分 

分 类 号：R284.1[医药卫生—中药学]