舒芬太尼复合纳布啡用于剖宫产术后静脉自控镇痛的效果  

Effect of Sufentanil combined with Naborphanine on intravenous controlled analgesia after cesarean section

作　　者：黄春阳 张永柏 HUANG Chunyang;ZHANG Yongbai(Department of Anesthesia,Midong District Hospital of Traditional Chinese Medicine in Urumqi,Xinjiang Uygur Autonomous Region,Urumqi831400,China)

机构地区：[1]乌鲁木齐市米东区中医医院麻醉科,新疆乌鲁木齐831400

出　　处：《中国当代医药》2023年第28期109-113,共5页China Modern Medicine

基　　金：新疆维吾尔自治区乌鲁木齐市卫生健康委科技计划项目(202054)。

摘　　要：目的探讨舒芬太尼复合纳布啡用于剖宫产术后静脉自控镇痛的效果。方法选取2020年11月至2022年11月乌鲁木齐市米东区中医医院收治的150例剖宫产术产妇作为研究对象,按照随机数字表法将其分为S组(50例)、N组(50例)与SN组(50例),S组采用舒芬太尼镇痛方法,N组采用纳布啡镇痛方法,SN组采用舒芬太尼复合纳布啡镇痛方法。比较三组的镇痛效果、镇静效果、不良反应发生情况、术后静脉自控镇痛按压次数。结果整体分析结果显示,S、N、SN组产妇的术后1、6、24、48 h的疼痛视觉模拟评分法(VAS)评分指标时间、组间、交互作用比较,差异有统计学意义(P<0.05)。术后6 h,S、N、SN组产妇的VAS评分均高于术后1 h;术后24 h,S、N、SN组产妇的VAS评分均高于术后1 h,且低于术后6 h;术后48 h,S、N、SN组产妇的VAS评分均低于术后6、24 h,差异有统计学意义(P<0.05)。SN组术后1、6、24、48 h的VAS评分低于S组、N组,差异有统计学意义(P<0.05);S组、N组术后1、6、24、48 h的VAS评分比较,差异无统计学意义(P>0.05)。整体分析结果显示,S、N、SN组产妇术后1、6、24、48 h的Ramsay镇静评分指标时间、组间、交互作用比较,差异无统计学意义(P>0.05)。术后6 h,S、N、SN组产妇的Ramsay评分均低于术后1 h;术后24 h,S、N、SN组产妇的Ramsay评分均低于术后1、6 h;术后48 h,S、N、SN组产妇的Ramsay评分均低于术后1、6、24 h,差异有统计学意义(P<0.05)。SN组、S组、N组术后1、6、24、48 h的Ramsay镇静评分比较,差异无统计学意义(P>0.05)。SN组术后不良反应总发生率低于S组、N组,差异有统计学意义(P<0.05);S组、N组术后不良反应总发生率比较,差异无统计学意义(P>0.05)。整体分析结果显示,S、N、SN组产妇术后1、6、24、48 h的术后静脉自控镇痛按压次数指标时间、组间、交互作用比较,差异有统计学意义(P<0.05)。术后6 h,S、N、SN组产妇静脉自控镇�Objective To investigate the effect of Sufentanil combined with Naborphanine on patient-controlled intravenous analgesia after cesarean section.Methods From November 2020 to November 2022,150 pregnant women undergoing cesarean section admitted to the Midong District Hospital of Traditional Chinese Medicine of Urumqi City were selected as the study subjects.They were divided into S group(50 cases),N group(50 cases),and SN group(50 cases)according to the method of random number table.S group was treated with Sufentanil,N group with Naborphanine,and SN group with Sufentanil combined with Naborphanine.The analgesic effect,sedative effect,occurrence of adverse reactions,and the number of postoperative patient-controlled intravenous analgesia compressions were compared among the three groups.Results The overall analysis results showed that there were statistically significant differences in visual analog scale(VAS)score index time,inter-group and interaction among patients in S,N and SN groups at 1,6,24 and 48 h after surgery(P<0.05).At 6 h after surgery,the VAS scores of S,N and SN groups were higher than those of 1 h after surgery;24 h after surgery,VAS scores in S,N and SN groups were higher than 1 h after surgery,and lower than 6 h after surgery;48 h after surgery,VAS scores in S,N and SN groups were lower than 6 and 24 h after surgery,the differences were statistically significant(P<0.05).The VAS scores of SN group at 1,6,24 and 48 h after operation were lower than those of S and N groups,and the differences were statistically significant(P<0.05).There was no significant difference in VAS scores between S group and N group at 1,6,24 and 48 h after operation(P>0.05).The overall analysis results showed that there was no statistical significance in Ramsay sedation score index time,inter-group and interaction at 1,6,24 and 48 h after surgery in S,N and SN groups(P>0.05).At 6 h after surgery,Ramsay scores in S,N and SN groups were lower than those in 1 h after surgery;24 h after surgery,Ramsay scores in S,N and SN grou

关 键 词：舒芬太尼 纳布啡 剖宫产 术后静脉自控镇痛 

分 类 号：R614[医药卫生—麻醉学]