非缺血型视网膜静脉阻塞的脉络膜视网膜静脉吻合术治疗  

Chorioretinal venous anastomosis for non-ischemic retinal vein occlusion

作　　者：王玉成 孙艳 王世武[1,2] 王少龙 邓爱军 WANG Yucheng;SUN Yan;WANG Shiwu;WANG Shaolong;DENG Aijun(School of Clinical Medicine,Weifang Medical University,Weifang,Shandong 261053,China;Eye Center of Affiliated Hospital of Weifang Medical University,Weifang,Shandong 261000,China;Ji'nan Huashi Eye Hospital,Ji'nan,Shandong 250014,China)

机构地区：[1]潍坊医学院临床医学院,山东潍坊261053 [2]潍坊医学院附属医院眼科中心,山东潍坊261000 [3]济南华视眼科医院,山东济南250014

出　　处：《安徽医药》2023年第11期2300-2306,共7页Anhui Medical and Pharmaceutical Journal

基　　金：山东省自然科学基金面上项目(ZR2020MH173)。

摘　　要：视网膜静脉阻塞(RVO)是指视网膜中央静脉或一级、二级分支的阻塞,多因素发病。临床中治疗方法有玻璃体腔药物注射、全身用药扩张视网膜血管、局部使用类固醇及非甾体类药物、溶栓、血液稀释、视网膜激光光凝术、玻璃体切割伴血管鞘膜切开、脉络膜视网膜静脉吻合(CRVA)术等。目前临床中常用治疗方法多针对RVO并发症,而脉络膜视网膜静脉吻合可通过静脉血管重塑将视网膜静脉血经脉络膜回流。许多国家的文献均有CRVA治疗RVO的相关报道,作为一种静脉血可以越过血管阻塞部位引流的治疗方式,从解剖学上解除视网膜静脉阻塞的部分因素达到治疗目的。该文从适应证、实施过程、术后效果评估、并发症及联合Anti-VEGF治疗等方面全面介绍了CRVA术,基于当前激光技术及玻璃体切割手术技术的发展,以期进一步回顾该治疗方法,为RVO临床治疗提供一种新的参考。Retinal vein occlusion(RVO)refers to the occlusion of central retinal vein or primary and secondary branches caused by multiple factors.Clinical treatments include intravitreal or systemic vasodilators application,local utilization of steroids and NSAID(non-steroidal anti-inflammatory drugs),thrombolysis,hemodilution,retinal laser photocoagulation,vitrectomy with vascular sheath incision,chorioretinal venous anastomosis(CRVA)and so on.At present,most treatment aim at RVO complications,while chorioretinal vein anastomosis can fundamentally reflux retinal vein blood through choroid by venous vascular remodeling.Reports about the treatment of retinal vein occlusion by chorioretinal anastomosis are numerous in varies of countries.As a treatment,CRVA can drain the venous blood skipping the thrombosis spot,thus partially relieves anatomical vascular occlusion to achieve a therapeutic purpose.In the current study,CRVA is introduced from the aspects of indications,implementation process,postoperative effect evaluation,complications and combination with anti-VEGF treatment.Based on the development of laser technology and vitrectomy,we hope to further review this treatment and provide a new reference for clinical treatment of RVO.

关 键 词：视网膜静脉阻塞 脉络膜视网膜静脉吻合 视网膜中央静脉阻塞 视网膜分支静脉阻塞 治疗 

分 类 号：R779.6[医药卫生—眼科]