一种新型甘脲荧光分子夹的合成及其性能研究  

Synthesis and Property of A Novel Fluorescent Glycoluril Molecular Clip

作　　者：朱超[1] 桂艳 陈晓春[1] 朱丽[1] 黄遥[1] ZHU Chao;GUI Yan;CHEN Xiaochun;ZHU Li;HUANG Yao(School of Chemical Engineering,Yunnan Open University,Kunming 650500,China)

机构地区：[1]云南开放大学化学工程学院,云南昆明650500

出　　处：《化学与生物工程》2023年第10期21-24,共4页Chemistry & Bioengineering

基　　金：云南省教育厅科学研究基金项目(2022J0594)。

摘　　要：甘脲分子夹是一类以甘脲为基本结构单元的“长臂型”超分子主体。设计合成了一种新型甘脲荧光分子夹,通过IR、^(1)HNMR、^(13)CNMR、MS对其结构进行了表征,并研究了其对金属离子的选择性。结果表明,甘脲荧光分子夹在216 nm、236 nm、265 nm、301 nm处均有较强的紫外吸收,在381 nm处有强的荧光发射峰;甘脲荧光分子夹对Ca^(2+)有很好的识别能力,Ca^(2+)浓度在0.1-3.2μmol•L^(-1)范围内与甘脲荧光分子夹的荧光强度呈良好的线性关系,线性相关系数R^(2)为0.989,检测限为0.047μmol•L^(-1)。甘脲荧光分子夹是一种高选择性、高灵敏度的Ca^(2+)荧光探针。Glycoluril molecular clip is a kind of″long arm″supramolecular host with glycoluril as basic structural unit.In this paper,we designed and synthesized a novel fluorescent glycoluril molecular clip,characterized its structure by IR,^(1)HNMR,^(13)CNMR,and MS,and studied the selectivity to metal ions.The results show that the fluorescent glycoluril molecular clip exhibits strong UV absorption at 216 nm,236 nm,265 nm,and 301 nm,and has a strong fluorescence emission intensity at 381 nm.The fluorescent glycoluril molecular clip has good recognition ability to Ca^(2+).There is a good linear relationship between the fluorescence intensity of the fluorescent glycoluril molecular clip with Ca^(2+)concentrations in the range of 0.1-3.2μmol•L^(-1) with a linear correlation coefficient R^(2) of 0.989 and a detection limit of 0.047μmol•L^(-1).Therefore,the fluorescent glycoluril molecular clip is a Ca^(2+)fluorescent probe with high selectivity and high sensitivity.

关 键 词：甘脲分子夹 荧光 分子识别 CA^(2+) 

分 类 号：O621.3[理学—有机化学]