中西医结合治疗2019新型冠状病毒肺炎临床疗效及预后相关性指标分析  

A study on clinical efficacy and prognostic correlation indexes in the treatment of 2019 novel coronavirus pneumonia by combining Chinese and Western medicine

作　　者：谭薇[1] TAN Wei(Department of Respiratory Medicine,Weifang People's Hospital,Weifang 261041,China)

机构地区：[1]潍坊市人民医院呼吸内科,山东潍坊261041

出　　处：《潍坊医学院学报》2023年第4期285-287,共3页Acta Academiae Medicinae Weifang

摘　　要：目的回顾性评价中西医结合治疗新型冠状病毒肺炎(COVID-19)的临床疗效。方法收集2020年2月~2021年2月潍坊市人民医院收治的80例新冠肺炎病例,实验组患者40例给予西药联合中药治疗,对照组患者40例给予西药治疗。观察患者经中西医结合治疗前后的临床症状、血常规、炎症因子等情况,明确中药在新冠治疗中的作用。结果实验组患者的主要症状如发热、干咳的消失率明显优于对照组,差异有统计学意义(P<0.05),但两组乏力消失率比较,差异无统计学意义(P>0.05)。实验组患者治疗后的白细胞(WBC)、C-反应蛋白(CRP)水平较治疗前降低(P<0.05),但中性粒细胞(NEUT)水平与治疗前比较,差异无统计学意义(P>0.05)。实验组、对照组患者白细胞介素-6(IL-6)、降钙素原(PCT)治疗后均下降(P<0.05)。结论中西医结合治疗可明显减轻COVID-19患者的临床症状,改善实验室检查指标,对COVID-19有治疗作用。Objective To evaluate the clinical efficacy of Chinese medicine in patients with COVID-19 retrospectively.Methods From February 2020 to February 2021,a total of 80 cases with novel coronavirus pneumonia admitted to the Weifang People's Hospital were enrolled,which were divided into the experimental group and the control group,with 40 cases in each group.The experimental group were given western medicine combined with Chinese herbal medicine,while the control group were given western medicine.The clinical symptoms,blood routine,inflammatory factors and other examination results were measured before and after Chinese medicine intervention,in order to clarify the role of Chinese medicine in the treatment of COVID-19.Results In the experimental group,the disappearance rate of main symptoms as fever and dry cough was significantly better than that of the control group,and the difference was statistically significant(P<0.05).In the experimental group,the levels of white blood cell(WBC)and C-reactive protein(CRP)decreased after treatment compared with those before treatment(P<0.05),but the difference in neutrophil(NEUT)levels was not statistically significant compared with those before treatment(P>0.05).The levels of interleukin-6(IL-6)and procalcitonin(PCT)decreased after treatment in both groups(P<0.05).Conclusion Chinese medicine can significantly alleviate the clinical symptoms and improve the laboratory test indicators in patients with COVID-19.

关 键 词：新型冠状病毒肺炎 中西医结合治疗 临床疗效 预后指标 

分 类 号：R563.1[医药卫生—呼吸系统]