糖尿病并发尿路感染病原菌及其影响因素  

Distribution of pathogens isolated from diabetes mellitus patients with urinary tract infection and influencing factors

作　　者：徐永丽 张红[2] 陆晓丽 XU Yong-li;ZHANG Hong;LU Xiao-li(Zhoukou Vocational and Technical College,Zhoukou,Henan 466000,China;不详)

机构地区：[1]周口职业技术学院,河南周口466000 [2]周口市中心医院内分泌科,河南周口466000 [3]周口市妇幼保健院护理部,河南周口466000

出　　处：《中华医院感染学杂志》2023年第17期2615-2618,共4页Chinese Journal of Nosocomiology

基　　金：河南省卫生健康委员会研究项目(豫卫科教[2021]33号文件)。

摘　　要：目的分析糖尿病患者尿路感染病原菌分布及其影响因素.方法选取2019年9月-2022年9月周口市中心医院收治的糖尿病患者342例纳入研究,回顾性收集患者临床资料,根据患者尿路感染情况分为无尿路感染组309例,尿路感染组33例.分析糖尿病合并尿路感染病原菌分布特征,单因素及多因素Logistic回归分析糖尿病合并尿路感染的影响因素.结果342例糖尿病患者尿路感染33例,感染率为9.65%;33例糖尿病合并尿路感染患者共分离出病原菌40株,其中革兰阴性菌22株,革兰阳性菌15株,真菌3株,占比分别为55.00%、37.50%、7.50%;多因素Logistic分析结果显示,女性患者、血清淀粉样蛋白A(SAA)水平升高、留置导尿管为糖尿病合并尿路感染的影响因素(P<0.05).结论糖尿病合并尿路感染发生率较高,主要感染病原菌为革兰阴性菌,糖尿病合并尿路感染的发生与女性患者、血清SAA水平、留置导尿管密切相关.OBJECTIVE To observe the distribution of pathogens isolated from the diabetes mellitus patients with urinary tract infection and analyze the influencing factors.METHODS A total of 342 patients with diabetes mellitus who were treated in Zhoukou Central Hospital from Sep 2019 to Sep 2022 were enrolled in the study and were divided into the no urinary tract infection group with 309 cases and the urinary tract infection group with 33 cases according to the status of urinary tract infection.The clinical data were retrospectively collected from the patients.The distribution of pathogens isolated from the diabetes mellitus patients complicated with urinary tract infection was observed.Univariate analysis and multivariate logistic regression analysis were performed for the influencing factors for the urinary tract infection in the diabetes mellitus.RESULTS Of the 342 diabetes mellitus,33 had urinary tract infection,with the infection rate 9.65%.Totally 40 strains of pathogens were isolated from the 33 diabetes mellitus patients complicated with urinary tract infection,22(55.00%)of which were gram-negative bacteria,15(37.50%)were gram-positive bacteria,and 3(7.50%)were fungi.Multivariate logistic analysis showed that female patient,rise of serum amyloid A(SAA)and urinary catheter indwelling were the influencing factors for the urinary tract infection in the diabetes mellitus patients(P<O.05).CONCLUSION The incidence of urinary tract infection is high among the patients with diabetes mellitus.The gram-negative bacteria are dominant among the pathogens causing the infection.The incidence of urinary tract infection in the patients with diabetes mellitus is closely associated with the female patient,serum SAA level and urinary catheter indwelling.

关 键 词：糖尿病 尿路感染 病原菌 TOLL样受体4 影响因素 

分 类 号：R587.1[医药卫生—内分泌]