小儿肺炎不同感染病原体类型外周血WBC和血清CRP、PCT水平特点及分析  

Characteristics and Analysis of Peripheral Blood WBC and Serum CRP and PCT Levels in Children with Different Types of Infectious Pathogens

作　　者：潘祥龙 李寿军 崔文权 PAN Xianglong;LI Shoujun;CUI Wenquan(Department of Pediatrics,Yizheng People's Hospital,Yizheng,Jiangsu Province,211400 China)

机构地区：[1]江苏省仪征市人民医院儿科,江苏仪征211400

出　　处：《系统医学》2023年第13期150-153,共4页Systems Medicine

摘　　要：目的探讨小儿肺炎不同感染病原体类型外周血白细胞计数(white blood cell count,WBC)、血清C反应蛋白(serum C-reactive protein,CRP)、降钙素原(procalcitonin,PCT)的水平特点。方法选择2021年1月—2022年12月仪征市人民医院收诊治疗的小儿肺炎患儿142例作为观察组,其中包括48例细菌性肺炎患儿、47例支原体肺炎患儿、47例病毒性肺炎患儿,选择同期于本院接受体检的健康儿童48例作为对照组,均进行外周血WBC、血清CRP、PCT指标检测,对比观察组不同感染病原体类型患儿与对照组检查结果差异,同时结合观察组肺炎患儿病情程度分析3项指标检查结果的差异性。结果细菌性肺炎患儿WBC、CRP、PCT均高于支原体肺炎、病毒性肺炎患儿及健康体检儿童,差异有统计学意义(P<0.05)。另外,重症肺炎患儿外周血WBC水平(14.01±2.38)×109/L、血清CRP水平(60.38±5.29)mg/L、PCT水平(3.81±0.55)ng/mL高于轻症肺炎患儿,差异有统计学意义(t=14.982、48.368、42.067,P<0.05)。结论临床可通过检测外周血WBC、血清CRP、PCT水平用于鉴别诊断不同感染病原体类型的小儿肺炎疾病,同时辅助鉴别病情程度,为临床提供数据支持,值得运用推广。Objective To investigate the characteristics of peripheral blood white blood cell count(WBC),serum C-reactive protein(CRP)and procalcitonin(PCT)in children with different infectious pathogens.Methods A total of 142 children with pneumonia who were admitted to Yizheng People's Hospital from January 2021 to December 2022 were selected as the observation group,including 48 children with bacterial pneumonia,47 children with mycoplasma pneu⁃monia,and 47 children with viral pneumonia.48 healthy children who underwent physical examination in our hospital during the same period were selected as the control group.Peripheral blood WBC,serum CRP,and PCT indicators were detected.The differences in the results of the children with different types of infectious pathogens in the observa⁃tion group and the control group were compared.At the same time,the differences in the results of the three indicators were analyzed in combination with the severity of pneumonia in the observation group.Results The levels of WBC,CRP,PCT in children with bacterial pneumonia were higher than those in children with mycoplasma pneumonia,viral pneumonia and healthy children,and the differences were statistically significant(P<0.05).In addition,the peripheral blood WBC level(14.01±2.38)×10^(9)/L,serum CRP level(60.38±5.29)mg/L and PCT level(3.81±0.55)ng/mL in chil⁃dren with severe pneumonia were higher than those in children with mild pneumonia,and the differences were statisti⁃cally significant(t=14.982,48.368,42.067,P<0.05).Conclusion Clinical detection of peripheral blood WBC,serum CRP and PCT levels can be used to differentiate and diagnose pediatric pneumonia diseases with different types of infectious pathogens,and at the same time assist in differentiating the severity of the disease,providing clinical data sup⁃port,and worthy of application and promotion.

关 键 词：小儿肺炎 不同感染病原体 外周血 血清CRP 

分 类 号：R563[医药卫生—呼吸系统]