鼓室注射地塞米松治疗难治性梅尼埃病的临床分析  

Clinical Analysis of Tympanic Injection of Dexamethasone for Treatment of Refractory Meniere's Disease

作　　者：周莹 李伟 ZHOU Ying;LI Wei(Department of Otorhinolaryngology,Sanming First Hospital Affiliated to Fujian Medical University,Sanming,Fujian Province,365000 China)

机构地区：[1]福建医科大学附属三明第一医院耳鼻喉科,福建三明365000

出　　处：《中外医疗》2023年第22期115-118,127,共5页China & Foreign Medical Treatment

摘　　要：目的分析探讨鼓室注射地塞米松治疗难治性梅尼埃病的临床价值。方法选取2018年4月—2021年4月福建医科大学附属三明第一医院收治的难治性梅尼埃病患者50例为研究对象,按照随机数表法分成对照组与观察组,各25例。对照组进行耳后注射地塞米松治疗,观察组进行耳内镜下鼓室注射地塞米松治疗,对比两组治疗效果。结果观察组改善率高于对照组,差异有统计学意义(P<0.05)。治疗后,观察组眩晕发作的严重程度及对日常生活的影响评分(1.02±0.65)分低于对照组(2.89±0.70)分,差异有统计学意义(t=9.788,P<0.05)。两组并发症发生率对比,差异无统计学意义(P>0.05)。结论鼓室注射地塞米松对于治疗难治性梅尼埃病效果好、并发症少,具有较好临床应用价值。Objective To analyze and explore the clinical value of tympanic chamber injection of dexamethasone in the treatment of refractory Meniere´s disease.Methods 50 patients with refractory Meniere´s disease admitted to San-ming First Hospital Affiliated to Fujian Medical University from April 2018 to April 2021 were selected as the study subjects.They were randomly divided into a control group and an observation group,with 25 patients in each group.The control group received retroauricular injection of dexamethasone,while the observation group received endoscopic tympanic injection of dexamethasone.The therapeutic effects of the two groups were compared.Results The improve-ment rate of the observation group was higher than that of the control group,and the difference was statistically signifi-cant(P<0.05).After treatment,the severity of dizziness and its impact on daily life score(1.02±0.65)points in the ob-servation group was lower than that in the control group(2.89±0.70)points,the difference was statistically significant(t=9.788,P<0.05).There was no statistically significant difference in the incidence of complications between the two groups(P>0.05).Conclusion The tympanic chamber injection of dexamethasone is effective in the treatment of refrac-tory Meniere´s disease with few complications,and has high clinical application value.

关 键 词：鼓室 地塞米松 难治性 梅尼埃病 

分 类 号：R5[医药卫生—内科学]