经鼻高流量湿化氧疗治疗慢性阻塞性肺疾病急性加重合并Ⅱ型呼吸衰竭患者的有效性评价  

Effect Evaluation of Nasal High Flow Humidification Oxygen Therapy for Acute Exacerbation of Chronic Obstructive Pulmonary Disease with Type Ⅱ Respiratory Failure

作　　者：孙建芳[1] 牛海英[1] 张冬[1] 赵刚[1] 何慧洁[1] SUN Jianfang;NIU Haiying;ZHANG Dong;ZHAO Gang;HE Huijie(Respiratory and Critical Care Department,Baotou Medical College the First Affiliated Hospital,Baotou,Inner Mongolia 014010)

机构地区：[1]包头医学院第一附属医院呼吸与危重症科,内蒙古包头014010

出　　处：《智慧健康》2023年第18期181-184,共4页Smart Healthcare

基　　金：包头医学院科学研究基金项目(青苗计划)《经鼻高流量湿化吸氧治疗慢性阻塞性肺疾病急性加重合并II型呼吸衰竭的临床观察》(项目编号:BYJJ-QM-2018017)。

摘　　要：目的 评价经鼻高流量湿化氧疗(HHFNC)治疗慢性阻塞性肺疾病急性加重(AECOPD)合并Ⅱ型呼吸衰竭患者的有效性。方法 取本院2018年10月-2021月6月患者50例,随机分为对照组(25例)和观察组(25例)。分别以无创性正压通气(NIPPV)与HHFNC治疗,比较效果。结果 与对照组比较,观察组治疗后的总有效率较高,SpO2与PaO2指标较高,PaCO_(2)较低,肺功能指标较高(P<0.05)。结论 临床常规对症治疗对于AECOPD合并Ⅱ型呼吸衰竭患者所能够发挥的作用比较有限,以HHFNC辅助治疗能够促进肺功能及血气分析改善,有利于患者获得更好的康复效果。Objective To evaluate effect of nasal high flow humidification oxygen therapy(HHFNC)in treatment of acute exacerbation of chronic obstructive pulmonary disease(AECOPD)with type II Respiratory failure.Methods The paper chose 50 patients in our hospital from October 2018 to June 2021,and divided them into control group and observation group randomly(25 cases/group).Effect of non-invasive positive pressure ventilation(NIPPV)and HHFNC treatment was compared respectively.Results Observation group had higher total effective rate than control group after treatment,with higher SpO_(2) and PaO_(2) indicators,lower PaCO_(2) and higher lung function indicators(P<0.05).Conclusion Clinical routine symptomatic treatment can play limited role in AECOPD patients with type II respiratory failure.HHFNC adjuvant treatment can improve lung function and blood gas analysis,which is conducive to better rehabilitation of patients.

关 键 词：经鼻高流量湿化氧疗 无创性正压通气 慢性阻塞性肺疾病急性加重 Ⅱ型呼吸衰竭 有效率 

分 类 号：R563.9[医药卫生—呼吸系统] R563.8[医药卫生—内科学]