“三部六病”调神平亢汤治疗溢脉型失眠的临床观察  

Clinical observation of"Sanbu Liubing"Tiaoshen Pingkang Decoction in treating spillway insomnia

作　　者：牛栋良 丁庆学 李嵘 王荣林 Niu Dong-liang;Ding Qing-xue;Li Rong;Wang Rong-lin(Department of Spleen,Stomach and Hepatobiliary,Hebi Hospital of Traditional Chinese Medicine,Hebi 458030,Henan,China;Department of Encephalopathy,Qixian Hospital of Traditional Chinese Medicine,Qixian 456750,Henan China)

机构地区：[1]河南省鹤壁市中医院脾胃肝胆科,河南鹤壁458030 [2]河南省淇县中医院脑病科,河南淇县456750

出　　处：《四川生理科学杂志》2023年第10期1861-1864,共4页Sichuan Journal of Physiological Sciences

摘　　要：目的:观察“三部六病”调神平亢汤治疗溢脉型失眠患者的临床疗效及其对中医证候积分、睡眠质量及睡眠脑电图的影响。方法:选取2021年3月至2022年11月期间我科收治的89例溢脉型失眠患者作为研究对象,采用随机数字表法分为西药组(n=44)和联合组(n=45)。西药组口服艾司唑仑治疗,联合组在西药组的基础上增加服用“三部六病”调神平亢汤治疗。对比两组患者的临床疗效,中医证候积分,匹兹堡睡眠质量评分以及睡眠脑电图情况。结果:治疗后,联合组总有效率明显高于西药组(P<0.05);治疗后,两组患者中医证候总积分、睡眠质量评分均明显下降,且联合组明显低于西药组(P<0.05);两组患者睡眠潜伏期明显缩短,且联合组明显短于西药组(P<0.05);两组觉醒时间虽明显缩短,但联合组觉醒时间较西药组差异不具统计学意义(P>0.05);两组患者总睡眠时间、睡眠效率均明显增加,且联合组明显高于西药组(P<0.05);西药组REM睡眠时间明显降低(P<0.05),联合组REM睡眠时间无明显变化(P>0.05)。两组不良反应发生率无明显差异。结论:“三部六病”调心神平亢汤联合艾司唑仑能有效改善溢脉型失眠患者睡眠质量,减少入睡时间,增加睡眠时间,提高睡眠效率,临床疗效确切,值得临床推广应用。Objective:To observe the clinical efficacy of"Three parts and six diseases"Tiaoshen Pingkang Decoction in the treatment of patients with spillage syndrome and its influence on TCM syndrome score,sleep quality and sleep electroencephalogram.Method:Eighty-nine patients with spillage syndrome in our department from March 2021 to November 2022 were selected as research objects,and they were divided into western medicine group(n=44)and combined group(n=45)by random number table method.The western medicine group was treated with Esazolam orally,and the combined group was additionally treated with"Three parts and six diseases"Tiaoshen Pingkang decoction。The clinical efficacy,TCM syndrome score,Pittsburgh sleep quality score and sleep electroencephalogram were compared between the two groups.Results:After treatment,the total effective rate of combined group was significantly higher than that of western medicine group(P<0.05).After treatment,the total TCM syndrome score and sleep quality score of 2 groups were significantly decreased,and the combined group was significantly lower than the western medicine group(P<0.05).The sleep latency of the two groups was significantly shortened,and the combined group was significantly shorter than the western medicine group(P<0.05).Although the awakening time of the two groups was significantly shortened,there was no statistical significance in the awakening time of the combined group compared with the western medicine group(P>0.05).The total sleep time and sleep efficiency of the two groups were significantly increased,and the combined group was significantly higher than the western medicine group(P<0.05).REM sleep time of western medicine group was significantly decreased(P<0.05),while that of combined group was not significantly changed(P>0.05).There was no significant difference in the incidence of adverse reactions between the two groups.Conclusion:"Three parts and six diseases"Tiaoshen Pingkang decoction combined with Esazolam can effectively improve the sleep quality of patie

关 键 词：三部六病 失眠 调神平亢汤 溢脉证 睡眠脑电图 

分 类 号：R256.23[医药卫生—中医内科学]