Responsive Hybrid Poly(vinyl alcohol)Hydrogel Membranes with Embedded Microgels as Valves  

作　　者：Zi-Lin Wang Di Huang Mei-Yu Zhang Xin-Xin Fu Ying Luo Lei Zou Si-Jia Gao Zhuo Zhao Ya-Fei Wang Yan Zhang Yong-Jun Zhang 

机构地区：[1]State Key Laboratory of Separation Membranes and Membrane Processes,School of Material Science and Engineering,Tiangong University,Tianjin,300387,China [2]Tianjin Key Laboratory of Extracorporeal Life Support for Critical Diseases,Institute of Hepatobiliary Disease,Nankai University Affiliated Third Center Hospital,Tianjin,300170,China [3]School of Chemistry,Tiangong University,Tianjin,300387,China

出　　处：《Chinese Journal of Polymer Science》2023年第10期1646-1655,共10页高分子科学（英文版）

基　　金：supported by the National Natural Science Foundation of China(Nos.22275137 and 82202342);Natural Science Foundation of Tianjin Municipal Science and Technology Commission(No.21JCYBJC01810).

摘　　要：The research and application of responsive materials have long been hampered by their complicated designs and tedious construction processes.Besides,many current responsive materials show retard or weak responsiveness.In this study,responsive hybrid poly(vinyl alcohol)hydrogel membranes with embedded poly(N-isopropylacrylamide-acrylic acid)microgels as valves were constructed by simple mixing and subsequent freezing-thawing process.In the structure of the membranes,the matrix poly(vinyl alcohol)chains thread through and entangle with the microgels,and the microgels are firmly constrained within the hybrid hydrogel network.The fast and sharp temperature responsiveness of the embedded microgels was largely retained and endowed the hydrogel membrane with excellent temperature and pH responsiveness.Moreover,the hydrogel membrane showed excellent fatigue resistance in both temperature and pH-responsive flux examination.This study presented the great potential of these hybrid hydrogel membranes in biomedical applications and provided a new strategy for the future design and construction of responsive biomaterials.

关 键 词：Poly(vinyl alcohol)hydrogel Microgels Hydrogel membrane 

分 类 号：TQ427.26[化学工程]