电针筋结点联合颈痛颗粒治疗颈源性头痛的临床研究  

Clinical Study on the Electroacupuncture at the Meridian Sinew Mass Combined with Jingtong Granules in the Treatment of Cervicogenic Headache Syndrome

作　　者：张婷[1] 齐婧[2] 刘侃[2] 王玥[3] ZHANG Ting;QI Jing;LIU Kan;WANG Yue(The First Dept.of Encephalopathy,The First Hospital of Hunan University of Chinese Medicine,Changsha 410007 Hunan,China;Dept.of Neurology,The First Hospital of Hunan University of Chinese Medicine,Changsha 410007 Hunan,China;Dept.of Pain Rehabilitation,The First Hospital of Hunan University of Chinese Medicine,Changsha 410007 Hunan,China)

机构地区：[1]湖南中医药大学第一附属医院脑病一科,湖南长沙410007 [2]湖南中医药大学第一附属医院神经内科,湖南长沙410007 [3]湖南中医药大学第一附属医院疼痛康复科,湖南长沙410007

出　　处：《广州中医药大学学报》2023年第9期2244-2250,共7页Journal of Guangzhou University of Traditional Chinese Medicine

基　　金：湖南省科卫联合资助项目(编号:2020JJ8066);湖南省教育厅资助项目(编号:21C0255);湖南省卫生健康委资助项目(编号:202203075671);湖南中医药大学一流学科开放基金项目(编号:2021ZYX20)。

摘　　要：【目的】观察电针筋结点联合颈痛颗粒治疗颈源性头痛(CEH)的临床疗效。【方法】将82例颈源性头痛的患者随机分为观察组和对照组,每组各41例。观察组给予电针筋结点联合颈痛颗粒治疗,对照组给予电针联合颈痛颗粒治疗,疗程均为4周。治疗4周后,观察2组患者治疗前后疼痛视觉模拟量表(VAS)评分和颈部主动关节活动度(ROM)的变化情况,以及椎动脉、基底动脉收缩期血流速度峰值(Vp)、平均血流速度(Vm)、舒张末期血流速度(Vd)的情况。比较2组患者治疗前后血清一氧化氮(NO)、内皮素1(ET-1)、白细胞介素6(IL-6)、白细胞介素4(IL-4)水平的变化情况。【结果】(1)治疗后,2组患者的VAS评分、头痛持续时间及发作频率明显改善(P<0.01),且观察组在改善VAS评分、头痛发作频率、头痛持续时间方面明显优于对照组,差异有统计学意义(P<0.01)。(2)治疗后,2组患者的主动关节活动度明显改善(P<0.01),且观察组在改善主动关节活动度方面明显优于对照组,差异有统计学意义(P<0.01)。(3)治疗后,2组患者的椎动脉、基底动脉收缩期血流Vp、Vm、Vd明显改善(P<0.01),且观察组在改善椎动脉、基底动脉收缩期血流Vp、Vm、Vd方面明显优于对照组,差异有统计学意义(P<0.01)。(4)治疗后,2组患者的血清NO、ET-1、IL-6、IL-4水平明显改善(P<0.01),且观察组在改善血清NO、ET-1、IL-6、IL-4水平方面明显优于对照组,差异有统计学意义(P<0.01)。【结论】电针筋结点联合颈痛颗粒治疗颈源性头痛,能明显改善患者的疼痛症状,增加患者颈部活动度,改善患者颈部血液循环,调节血清NO、ET-1、IL-6、IL-4水平,疗效显著。Objective To observe the clinical efficacy of electroacupuncture at the meridian sinew mass combined with Jingtong Granules in the treatment of cervicogenic headache syndrome(CEH).Methods Eighty-two patients with CEH were randomly divided into an observation group and a control group,with 41 cases in each group.The observation group was treated with electroacupuncture at the meridian sinew mass combined with Jingtong Granules,while the control group was treated with electroacupuncture combined with Jingtong Granules.Both groups of patients were treated for 4 weeks.After 4 weeks of treatment,changes in visual analogue scale(VAS)scores and active range of motion(ROM)of the neck,as well as peak systolic blood flow velocity(Vp)and mean blood flow velocity(Vm)of the vertebral and basilar arteries and end-diastolic blood flow velocity(Vd)were observed before and after treatment in the two groups.The serum nitric oxide(NO),endothelin-1(ET-1),enddiastolic flow velocity(Vd),interleukin-6(IL-6)and interleukin-4(IL-4)levels were compared before and after treatment in the two groups of patients.Results(1)After treatment,the VAS score,headache duration and attack frequency of the two groups were significantly improved(P<0.01),and the observation group was significantly superior to the control group in improving the VAS score,headache attack frequency and headache duration,and the difference was statistically significant(P<0.01).(2)After treatment,the active joint mobility of the two groups was significantly improved(P<0.01),and the observation group was significantly superior to the control group in improving the active ROM of joint,and the difference was statistically significant(P<0.01).(3)After treatment,the systolic blood flow Vp,Vm and Vd of the vertebral artery and basilar artery were significantly improved in the two groups(P<0.01),and the observation group was significantly superior to the control group in improving the systolic blood flow Vp,Vm and Vd of the vertebral artery and basilar artery,and the difference was

关 键 词：电针 经筋理论 筋结点 颈源性头痛 颈痛颗粒 临床观察 

分 类 号：R246.9[医药卫生—针灸推拿学]