常用癌因性疲乏患者报告结局工具及其临床应用的研究进展  

Research Progress on Commonly-Used Tools of Patient-Reported Outcomes for Patients with Cancer-Related Fatigue and Clinical Application of the Tools

作　　者：厉柯轩 蔡媛媛 谢舒 董佳倩 裘秀月[1] LI Ke-Xuan;CAI Yuan-Yuan;XIE Shu;DONG Jia-Qian;QIU Xiu-Yue(School of Nursing,Zhejiang Chinese Medical University,Hangzhou 310053 Zhejiang,China)

机构地区：[1]浙江中医药大学护理学院,浙江杭州310053

出　　处：《广州中医药大学学报》2023年第10期2683-2688,共6页Journal of Guangzhou University of Traditional Chinese Medicine

摘　　要：对常见的癌因性疲乏(cancer-related fatigue,CRF)患者报告结局(patient-reported outcomes,PRO)工具的特点、测量学属性及应用现状进行综述。根据涉及的维度,癌因性疲乏PRO测评工具可分为单维度PRO测评工具与多维度PRO测评工具两大类。与癌因性疲乏相关的单维度PRO测评工具主要有简明疲乏量表(Brief Fatigue Inventory,BFI)、视觉模拟疲乏量表(Visual Analogue Fatigue Scale,VAFS)和疲乏调查问卷(Fatigue Questionnaire,FQ);与癌因性疲乏相关的多维度PRO测评工具主要有多维疲劳症状清单简表(Multidimensional Fatigue Symptom Inventory-Short Form,MFSI-SF)、多维疲劳量表(Multidimensional Fatigue Inventory,MFI)、Piper疲乏量表(Piper Fatigue Scale,PFS)、疲乏症状量表(Fatigue Symptom Inventory,FSI)和癌症疲乏量表(Cancer Fatigue Scale,CFS)。在临床实践中,利用PRO工具能精准量化评估癌因性疲乏症状,科学辅助医疗决策的制定,促进医患沟通,提升照护质量。现有的PRO工具多起源于国外,聚焦于西医领域,主要从癌因性疲乏的严重程度、持续时间、对日常生活质量的影响等进行评估,对中医领域中癌因性疲乏辨证相关的寒热虚实、气血阴阳尚未涉及。未来可在中医理论指导下,进一步研制与中医辨证分型相适应的具有本土化特色的PRO工具,促进PRO工具在中医药治疗癌症领域中的应用。A review of the characteristics,measurement properties and current application of the common patientreported outcomes(PRO)tools for cancer-related fatigue(CRF)is presented in this article.According to the dimensions involved,PRO assessment tools for CRF can be divided into two categories,i.e.,unidimensional PRO assessment tools and multidimensional PRO assessment tools.The main unidimensional PRO assessment tools for CRF are the Brief Fatigue Inventory(BFI),Visual Analogue Fatigue Scale(VAFS)and Fatigue Questionnaire(FQ);the main multidimensional PRO assessment tools for CRF are the Multidimensional Fatigue Symptom Inventory-Short Form(MFSI-SF),Multidimensional Fatigue Inventory(MFI),Piper Fatigue Scale(PFS),Fatigue Symptom Inventory(FSI)and Cancer Fatigue Scale(CFS).In clinical practice,PRO tools can be used to accurately and quantitatively assess the symptoms of CRF,which will help to scientifically make medical decision,benefit to patient-physician communication and improve the quality of medical care.Most of the existing PRO tools originate from overseas and focus on the western medicine issues of assessing the severity of CRF,duration of CRF,and the impact of CRF on the quality of daily life,while have no concerns of the items of cold and heat,deficiency and excess,qi and blood,and yin and yang associated with the syndrome differentiation of CRF in the field of traditional Chinese medicine(TCM).In the future,it is expected to establish the native PRO tools for CRF which are compatible with TCM syndrome differentiation and classification under the guidance of TCM theory,and to promote the application of PRO tools in the field of TCM for cancer treatment.

关 键 词：癌因性疲乏(CRF) 患者报告结局(PRO) 测评工具 综述 

分 类 号：R195.1[医药卫生—卫生统计学] R2-03[医药卫生—卫生事业管理]