超声造影联合超声弹性成像在甲状腺TI-RADS 3~4类结节中的应用  

Application of CEUS Combined with Ultrasound Elastography in Thyroid TI-RADS 3-4 Nodules

作　　者：宋建明[1] 陈花[1] 游宇光[1] 陈卫华[1] 叶军[1] 葛贻珑[1] 曾琪[1] Song Jianming;Chen Hua;You Yuguang;Chen Weihua;Ye Jun;Ge Yilong;Zeng Qi(Department of Ultrasound,The First Affiliated Hospital of Gannan Medical University,Ganzhou,Jiangxi 341000,China)

机构地区：[1]赣南医学院第一附属医院超声医学科,江西省赣州市341000

出　　处：《中国超声医学杂志》2023年第9期969-973,共5页Chinese Journal of Ultrasound in Medicine

基　　金：江西省卫生健康委员会科技计划项目(No.202210931)。

摘　　要：目的探讨超声造影(CEUS)联合超声弹性成像(UE)在甲状腺TI-RADS 3~4类结节中的应用价值。方法回顾性分析145例甲状腺患者甲状腺影像报告和数据系统(TI-RADS)3~4类结节共156个,应用UE进行弹性分级,检测弹性应变率比值(SR),再进行CEUS检查,分别计算UE、CEUS,以及两者联合对本组结节良恶性诊断的灵敏度、特异度、准确度,构建受试者工作特征(ROC)曲线分析3种方法对本组甲状腺结节良恶性的诊断价值。结果本组甲状腺良恶性结节CEUS增强水平、增强分布、增强环、消退情况等存在不同表现,差异具有统计学意义;CEUS联合UE对本组甲状腺结节良恶性诊断的灵敏度、特异度、准确度、阳性预测值、阴性预测值及曲线下面积(AUC)高于单一诊断法。结论CEUS联合UE对甲状腺TI-RADS 3~4类结节良恶性判断具有较好的诊断价值。Objective To investigate the application value of contrast-enhanced ultrasound(CEUS)combined with ultrasound elastography(UE)in thyroid imaging reporting and data system(TI-RADS)3 and 4 nodules.Methods Selected 156 nodules in 145 cases of TI-RADS 3 and 4 thyroid patients were included and analyzed retrospectively.UE was used to calculate elastic grading and elastic strain rate ratio(SR),followed by CEUS examination.The sensitivity,specificity and accuracy of UE,CEUS and combined method for diagnosis of benign and malignant nodules.Area under the curve(AUC)curve was drawn to assess the predictive value of the three modes for benign and malignant thyroid nodules.Results The difference of benign and malignant nodules in enhancement level,enhancement distribution,enhancement ring and regression in the CEUS group were statistically significant;the sensitivity,specificity,accuracy,positive predictive value,negative predictive value,and AUC by CEUS combined with UE were higher than that of the single method.Conclusions CEUS combined with UE has a good diagnostic value in the differential diagnosis of benign and malignant thyroid TI-RADS 3 and 4 nodules.

关 键 词：甲状腺结节 超声造影 弹性成像 

分 类 号：R445.1[医药卫生—影像医学与核医学] R736.1[医药卫生—诊断学] R581[医药卫生—临床医学]