心脏磁共振在心脏淀粉样变性中的应用进展  

Application of Cardiac Magnetic Resonance in Cardiac Amyloidosis

作　　者：侯为洁 龚艳君[1] HOU Weijie;GONG Yanjun(Department of Cardiology,Peking University First Hospital,Beijing 100034,China)

机构地区：[1]北京大学第一医院心内科,北京100034

出　　处：《心血管病学进展》2023年第9期796-799,共4页Advances in Cardiovascular Diseases

摘　　要：心脏淀粉样变性(CA)是指大量淀粉样纤维沉积于心肌细胞外间质,影响心脏结构与功能的一种严重疾病,随着病程进展,最终发展为严重的难治性心力衰竭。CA发病率低,目前诊断不足,且与肥厚型心肌病、高血压心脏病、主动脉瓣狭窄等引起心肌肥厚的疾病难以鉴别。心脏磁共振具有无创、软组织分辨率高、无电离辐射等优势,其中心肌延迟强化、T1 mapping、细胞外间质容积、T2 mapping、心脏磁共振特征跟踪以及弥散张量成像在CA的临床诊断、疾病分层和预后评估中有重要作用。现就心脏磁共振在CA中的应用进展做一综述。Cardiac amyloidosis(CA) is a serious disease in which a large number of amyloid fibers are deposited in the extracellular matrix of the myocardium,affecting the structure and function of the heart.With the progression of the disease,it eventually develops into severe refractory heart failure.The incidence rate of CA is low.At present,the diagnosis is insufficient,and it is difficult to distinguish CA from hypertrophic cardiomyopathy,hypertensive heart disease,aortic valve stenosis and other diseases that cause cardiac hypertrophy.Because of its non-invasive,high soft tissue resolution,non-radiation and other advantages,cardiac magnetic resonance such as late gadolinium enhancement,T1 mapping,extracellular volume,T2 mapping,cardiac magnetic resonance feature tracking and diffusion tensor imaging play an important role in the clinical diagnosis,disease stratification and prognosis evaluation of CA.This article will review the application progress of cardiac magnetic resonance in CA.

关 键 词：心脏磁共振 心脏淀粉样变性 心肌延迟强化 Native T1 细胞外间质容积 T2 mapping 心脏磁共振特征跟踪 弥散张量成像 

分 类 号：R445.2[医药卫生—影像医学与核医学] R541[医药卫生—诊断学]