生物基抗菌水凝胶研究进展  

Research progress of biobased antibacterial hydrogels

作　　者：戎旭辉 陈鲁正 娄江 丁大森 韩文佳[1] RONG Xuhui;CHEN Luzheng;LOU Jiang;DING Dasen;HAN Wenjia(State Key Laboratory of Biobased Material and Green Papermaking,Qilu University of Technology(Shandong Academy of Sciences),Jinan 250353,China;Shandong Sinocera Functional Material CO.,LTD.,DongYing 257092,China)

机构地区：[1]齐鲁工业大学(山东省科学院)生物基材料与绿色造纸国家重点实验室,济南250353 [2]山东国瓷功能材料股份有限公司,东营257092

出　　处：《复合材料学报》2023年第9期4972-4984,共13页Acta Materiae Compositae Sinica

基　　金：山东省重点研发计划(2021CXGC011002);山东省齐鲁工业大学(山东省科学院)揭榜制项目(2022JBZ01-05);济南市“新高校20条”资助项目科研带头人工作室(20228103)。

摘　　要：致病微生物所引起的感染一直以来都威胁着全世界人类的健康,抗菌材料在某种情况下可以被视为抗生素的替代品,其中抗菌水凝胶就是一类重要的高分子抗菌材料。生物基抗菌水凝胶根据基体种类不同主要分为壳聚糖基、纤维素基、淀粉基、海藻酸钠基、蛋白质基等,这些基质在自然界具有高丰度,生物相容性及生物可降解性的优点,是制备抗菌水凝胶的理想材料。本文综述了近年来生物基抗菌水凝胶的发展现状及应用领域,着重从生物基抗菌水凝胶的种类、制备和应用3个方面来阐述,最后对生物基抗菌水凝胶所面临的挑战及未来的发展趋势进行了总结和展望。Infections caused by pathogenic microorganisms have long been a threat to human health around the world.The development of antibacterial biomaterials can be regarded as a substitute for antibiotics in some cases,among which antibacterial hydrogels are an important class of macromolecular antibacterial agents.Bio-based antibacterial hydrogels can be divided into chitosan,cellulose,starch,sodium alginate and protein-based antibacterial hydrogels according to different matrix types.These substrates have high abundance,good biocompatibility and biodegradability in nature,and are ideal materials for preparing antibacterial hydrogels.In this paper,the development status and application fields of bio-based antibacterial hydrogels in recent years were reviewed,mainly from the types,preparation and application of bio-based antibacterial hydrogels.Finally,the challenges faced by biobased antibacterial hydrogels and the future development trend were summarized and prospeced.

关 键 词：抗菌材料 生物基复合材料 水凝胶 抗菌功能敷料 

分 类 号：TB3333[一般工业技术—材料科学与工程]