定制化PEEK颈椎椎间融合器的设计  

Design of Individualized PEEK Cervical Interbody Fusion Cage

作　　者：迪力努尔·塔尔江 乌日开西·艾依提[1] 滕勇 Diinuer Taerjiang;Wurikaixi Aiyiti;TENG Yong(School of Mechanical Engineering,Xinjiang University,Xinjiang Urumqi 830047,China;PLA Orthopedics Center,General Hospital of Xinjiang Military Region,Xinjiang Urumqi 830000,China)

机构地区：[1]新疆大学机械工程学院,新疆乌鲁木齐830047 [2]中国人民解放军新疆军区总医院全军骨科中心,新疆乌鲁木齐830000

出　　处：《机械设计与制造》2023年第10期170-173,共4页Machinery Design & Manufacture

基　　金：国家自然科学基金项目(52065063);新疆维吾尔自治区区域协同创新专项(科技援疆计划)项目(2019E0277)。

摘　　要：脊椎融合术中使用的传统椎间融合器是批量化生产的标准化产品,可能会导致植入的椎间融合器上下表面不能与相邻椎体的上下终板良好匹配。文中根据患者的CT数据设计了定制化的颈椎椎间融合器,椎间融合器的上下表面可与相邻椎体的上下终板良好的接触。针对1.5mm,2.5mm,3.5mm三种壁厚的椎间融合器进行了有限元分析,结果表明三种壁厚椎间融合器的最大应力都小于椎体皮质骨和聚醚醚酮(PEEK)材料的屈服强度。采用3D打印的方法制备了三种壁厚的PEEK试样进行压缩实验,结果表明三种壁厚的试样都能满足承载要求。壁厚1.5mm时,植骨孔的横截面积比壁厚2.5mm和3.5mm分别大20.2%,49.8%,适于制备椎间融合器。The standardized mass produced product traditional cage were applied to spinal fusion,which may lead to the failure of the upper and lower surfaces of the cage to match the endplates of adjacent vertebrae.Designed a customized cervical interbody fusion cage based on the CT data of the patients and the upper and lower surfaces of the cage can be in good contact with the end-plates of adjacent vertebral bodies.Finite element analysis of 1.5mm,2.5mm and 3.5mm three wall thicknesses of intervertebral fusion cage and the result shows that all maximum stresses were less than cortical bone and PEEK.3D printed of PEEK samples with three thickness,then based on the compression experiments the specimens with three wall thicknesses can meet the require-ments of bearing capacity.When the wall thickness was 1.5mm,the cross-sectional area of the bone graft hole was 20.2%and 49.8%larger than the wall thickness of 2.5mm and 3.5mm,respectively,which was suitable for the preparation of intervertebral fusion cage.

关 键 词：椎间融合器 聚醚醚铜 3D打印 有限元分析 

分 类 号：TH16[机械工程—机械制造及自动化] R318[医药卫生—生物医学工程]