核壳型NaYF_(4):Yb^(3+),Er^(3+)@SiO_(2)上转换纳米功能材料的制备与条件优化  

Preparation and optimization of core-shell NaYF_(4):Yb^(3+),Er^(3+)@SiO_(2)up-conversion nano functional materials

作　　者：彭微 白安琪 彭孔浩 殷慧 孟颖 李淑荣[1,2] 张凌燕 罗利霞[1,2] 孟佩俊 PENG Wei;BAI An-qi;PENG Kong-hao;YIN Hui;MENG Ying;LI Shu-rong;ZHANG Ling-yan;LUO Li-xia;MENG Pei-jun(School of Public Health,Baotou Medical College,Baotou,Inner Mongolia 014040,China;不详)

机构地区：[1]包头医学院公共卫生学院,内蒙古包头014040 [2]内蒙古自治区卫生检测与评价工程技术中心,内蒙古包头014040

出　　处：《现代预防医学》2023年第19期3606-3612,共7页Modern Preventive Medicine

基　　金：国家自然科学基金(81960601);内蒙古自治区高等学校青年科技英才支持项目(NJYT23026);内蒙古自治区自然科学基金(2021MS08055);内蒙古自治区卫生健康委医疗卫生科技计划项目(202201383);包头医学院“花蕾计划”项目(HLBTMC202223)。

摘　　要：采用溶剂热法合成稀土离子Yb^(3+)与Er^(3+)掺杂的NaYF_(4)上转换纳米颗粒(NaYF_(4):Yb^(3+),Er^(3+)),利用反相微乳液法对NaYF_(4):Yb^(3+),Er^(3+)进行二氧化硅包壳修饰得到核壳型NaYF_(4):Yb^(3+),Er^(3+)@SiO_(2),并对影响其材料结构、形貌和发光性能的反应条件表面活性剂(CO-520)浓度、正硅酸乙酯(TEOS)浓度与反应时间进行了优化。结果表明,当CO-520浓度为27mol/L、TEOS浓度为18mmol/L与反应时间为24h时合成的核壳型NaYF_(4):Yb^(3+),Er^(3+)@SiO_(2)壳层厚度均匀,分散性良好,尺寸均一,经980nm激光照射可在529、544与660nm三个特征峰处发射上转换荧光,其绿色荧光(544nm)最为明亮。本研究优化合成的性能优良的核壳型NaYF_(4):Yb^(3+),Er^(3+)@SiO_(2)稀土掺杂上转换纳米材料为其后续在生物医学、卫生检测等领域的应用奠定了坚实基础。Rare earth ion Yb^(3+)and Er^(3+)-doped NaYF_(4)up conversion nanoparticles(NaYF_(4):Yb^(3+),Er^(3+))were synthesized by solvothermal method,and core-shell NaYF_(4):Yb^(3+),Er^(3+)@SiO_(2)was obtained by silica envelope modification of NaYF_(4):Yb^(3+),Er^(3+)by inverse microemulsion method.The reaction conditions affecting the structure,morphology,and luminescence properties of NaYF_(4):Yb^(3+),Er^(3+)@SiO_(2)were optimized,such as the concentration of surfactant(CO-520),the concentration of ethyl orthosilicate(TEOS),and the reaction time.The results showed that when the concentration of CO-520 was 27mol/L,the concentration of TEOS was 18mmol/L and the reaction time was 24 h,the shell thickness of core-shell NaYF_(4):Yb^(3+),Er^(3+)@SiO_(2)was uniform,the dispersion was good,and the size was uniform.After 980nm laser irradiation,the up-conversion fluorescence can be emitted at the three characteristic peaks of 529544 and 660nm,and the green fluorescence(544nm)was the brightest.In this study,the optimized synthesis of core-shell NaYF_(4):Yb^(3+),Er^(3+)@SiO_(2)rare earth doped up conversion nanomaterials has laid a solid foundation for its subsequent applications in biomedical,health detection and other fields.

关 键 词：稀土掺杂上转换纳米材料 NaYF_(4):Yb^(3+) Er^(3+)@SiO_(2) 反相微乳液法 条件优化 

分 类 号：O65[理学—分析化学]