不同耳穴疗法对铂类化疗患者消化道症状及生活质量的影响  

Effects of different auricular point therapies on digestive symptoms and quality of life in patients undergoing platinum-based chemotherapy

作　　者：何燕燕 孙志岭 赵珍妮 张睿 冯韵 李嘉玮 HE Yanyan;SUN Zhiling;ZHAO Zhenni;ZHANG Rui;FENG Yun;LI Jiawei(School of Nursing,Nanjing University of Chinese Medicine,Nanjing 210023,China;Affiliated Hospital of Nanjing University of Chinese Medicine,Nanjing 210029,China)

机构地区：[1]School of Nursing,Nanjing University of Chinese Medicine,Nanjing 210023,China [2]Affiliated Hospital of Nanjing University of Chinese Medicine,Nanjing 210029,China

出　　处：《Journal of Acupuncture and Tuina Science》2023年第5期383-390,共8页针灸推拿医学（英文版）

基　　金：江苏省研究生科研与实践创新计划项目,No.SJCX22-0809,No.SJCX21-0667。

摘　　要：目的:比较耳穴揿针及耳穴贴压对铂类方案化疗患者消化道症状及生活质量的影响。方法:按照随机数字表法将96例铂类药物化疗患者随机分为三组,每组32例。对照组采用常规护理加5-羟色胺受体拮抗剂进行干预,其他两组分别在对照组的基础上加用耳穴揿针或耳穴贴压。观察三组患者急性及迟发性呕吐发生频次、恶心严重程度、食欲、生活质量及额外止吐药物追加率。结果:三组患者急性期呕吐频次、恶心严重程度及食欲的比较差异无统计学意义(P>0.05),延迟期呕吐频次及恶心严重程度比较差异有统计学意义(P<0.05),且耳穴揿针组疗效优于耳穴贴压组。三组患者延迟期食欲差异有统计学意义(P<0.05),耳穴揿针组及耳穴贴压组疗效均优于对照组(P<0.05),但耳穴揿针组及耳穴贴压组之间比较无统计学差异(P>0.05)。三组患者急性期及延迟期恶心呕吐生活功能指数比较均具有统计学意义(P<0.05),且耳穴揿针组优于耳穴贴压组(P<0.05);对照组额外止吐药物追加率高于另外两组(P<0.05)。结论:在常规护理及使用5-羟色胺拮抗剂的基础上进行耳穴揿针或耳穴贴压均能降低铂类方案化疗患者的延迟期呕吐频次和恶心严重程度,增加患者食欲,但对急性期消化道症状无明显影响,且耳穴揿针整体疗效优于耳穴贴压。耳穴揿针及耳穴贴压均可有效提高化疗患者的生活质量,减少患者额外止吐药物的使用。Objective:To compare the effects of auricular point intradermal needling with auricular point sticking on digestive symptoms and quality of life in patients undergoing platinum-based chemotherapy regimens.Methods:Ninety-six patients receiving platinum-based chemotherapy were randomly assigned to three groups using the random number table method,with 32 cases in each group.The control group received conventional nursing care plus 5-hydroxytryptamine receptor antagonist,and the other two groups received additional auricular point intradermal needling or sticking.For the three groups of participants,the acute and delayed vomiting and nausea severity,quality of life,and the additional antiemetic consumption rate were observed.Results:The three groups had no significant differences in the acute vomiting frequency and nausea severity and appetite(P>0.05)but had significant differences in the delayed vomiting frequency and nausea severity(P<0.05);the auricular point intradermal needling group won over the auricular point sticking group.The three groups showed significant differences in comparing the appetite in the delayed stage(P<0.05);both auricular point intradermal needling and sticking groups showed advantages over the control group(P<0.05),but no significant difference existed between the auricular point intradermal needling and sticking groups(P>0.05).There were significant differences in comparing the functional living index-emesis(FLIE)score in both acute and delayed stages among the three groups(P<0.05)and the result favored the auricular point intradermal needling group over the auricular point sticking group(P<0.05).The additional antiemetic consumption rate was higher in the control group than in the other groups(P<0.05).Conclusion:Based on the conventional nursing and 5-hydroxytryptamine receptor antagonist,adding either auricular point intradermal needling or auricular point sticking can lower the vomiting frequency and nausea severity in the delayed stage and improve appetite in patients receiving platin

关 键 词：耳针 皮内针疗法 耳穴贴压 恶心 呕吐 生活质量 药物疗法 药物相关的副作用和不良反应 

分 类 号：R245.3[医药卫生—针灸推拿学]