基于激光散斑衬比成像技术探寻原发性痛经患者足三阴经特异性反应穴位  

Seeking specific response points from the three Yin meridians of foot using laser speckle contrast imaging in patients with primary dysmenorrhea

作　　者：范玺胜 魏盼盼 师旭亮 宋晓丹 张明健 张俊茶 刘君 潘丽佳 杜潇怡 佘延芬 FAN Xisheng;WEI Panpan;SHI Xuliang;SONG Xiaodan;ZHANG Mingjian;ZHANG Juncha;LIU Jun;PAN Lijia;DU Xiaoyi;SHE Yanfen(School of Acupuncture-moxibustion and Tuina,Hebei University of Chinese Medicine,Shijiazhuang 050200,China;Hebei International Joint Research Center for Dominant Diseases in Chinese Medicine and Acupuncture,Shijiazhuang 050200,China;Graduate School of Hebei University of Chinese Medicine,Shijiazhuang 050091,China;Shijiazhuang Maternity and Child Healthcare Hospital,Shijiazhuang 050051,China)

机构地区：[1]School of Acupuncture-moxibustion and Tuina,Hebei University of Chinese Medicine,Shijiazhuang 050200,China [2]Hebei International Joint Research Center for Dominant Diseases in Chinese Medicine and Acupuncture,Shijiazhuang 050200,China [3]Graduate School of Hebei University of Chinese Medicine,Shijiazhuang 050091,China [4]Shijiazhuang Maternity and Child Healthcare Hospital,Shijiazhuang 050051,China

出　　处：《Journal of Acupuncture and Tuina Science》2023年第5期405-412,共8页针灸推拿医学（英文版）

基　　金：国家自然科学基金地区项目,No.81573884,No.81973755,No.81603542;河北中医学院优秀创新团队建设项目,No.JTZ2020008。

摘　　要：目的:通过激光散斑衬比成像(LSCI)技术观察原发性痛经(PD)患者足三阴经不同穴位的血流灌注量(PU),探寻PD患者体表特异性反应穴位。方法:选择PD患者80名为PD组,正常女大学生80名作为正常组。在一个月经周期内(经前、经期、经后3 d),采用LSCI系统对每名受试者的双侧太溪、太白、太冲、水泉、地机、中都、三阴交、血海和非经非穴处进行PU检测。定位者、操作者和统计人员均不了解分组情况。结局指标为测试点的PU。结果:与正常组比较,经前PD组右侧太溪PU明显升高(P<0.05);经期PD组双侧中都和右侧地机的PU均升高(P<0.05)。其他时间点的两组各测试点PU均无统计学差异(P>0.05)。结论:与健康受试者相比,PD患者的太溪、地机、中都局部PU在月经周期的特定时期会出现特异性变化,可为临床针灸治疗PD提供选穴参考。Objective:To seek specific response points on the body surface of patients with primary dysmenorrhea(PD)by observing blood perfusion unit(PU)at different points of the three Yin meridians of foot using laser speckle contrast imaging(LSCI).Methods:Eighty PD patients were recruited as a PD group,and 80 healthy female undergraduates were taken as a normal group.During one menstrual cycle(before menstruation,during menstruation,and 3 d after menstruation),each participant was examined using the LSCI system to determine PU at bilateral Taixi(KI3),Taibai(SP3),Taichong(LR3),Shuiquan(KI5),Diji(SP8),Zhongdu(LR6),Sanyinjiao(SP6),and Xuehai(SP10)and non-acupuncture points.The researchers in charge of point location,operation,and statistical analysis were not aware of grouping.PU at the detection spots was taken as the outcome measure.Results:Compared with the normal group,the PD group showed increases in PU at right Taixi(KI3)before menstruation(P<0.05)and at bilateral Zhongdu(LR6)and right Diji(SP8)during menstruation(P<0.05).At the other time points,significance was not found between the two groups in comparing PU at the detected spots.Conclusion:Compared with healthy participants,PD patients present specific changes in PU at Taixi(KI3),Diji(SP8),and Zhongdu(LR6)at specific time points during the menstrual cycle,which provides a reference for acupuncturemoxibustion treatment of PD in clinical settings.

关 键 词：穴位 足三阴经 原穴 郄穴 痛经 激光散斑衬比成像 微循环 灌注 

分 类 号：R246.3[医药卫生—针灸推拿学]