硝基苯中毒的研究进展  

Research Advances in Nitrobenzene Poisoning

作　　者：王志浩 杜宇[1] 陈绍璞 郑丽娜 刘琪 WANG Zhi-hao;DU Yu;CHEN Shao-pu;ZHENG Li-na;LIU Qi(Department of Forensic Pathology,Criminal Investigation Police University of China,Shenyang 110854,China)

机构地区：[1]中国刑事警察学院法医病理教研室,辽宁沈阳110854

出　　处：《化工管理》2023年第30期73-76,共4页Chemical Engineering Management

基　　金：公安部技术研究计划项目(2022JSYJC25,2017JSYJC06);中国刑事警察学院研究生创新能力提升项目(2021YCYB38,2021YCYB39,2022YCZD03)。

摘　　要：硝基苯是重要的工业原料,中毒相对罕见。硝基苯进入人体后将血红蛋白氧化为高铁血红蛋白,可引起溶血,并继发脑、心、肺、肝、肾等多器官系统性损害。文章从硝基苯用途、中毒原因、中毒症状、组织病理学变化、中毒机理以及救治等方面对硝基苯急性中毒研究的相关进展进行系统综述,以期为硝基苯中毒的预防、救治以及鉴定工作提供参考。Nitrobenzene is an important industrial raw material and poisoning is relatively rare.After entering the body,nitrobenzene oxidizes hemoglobin to methemoglobin,which can cause hemolysis and secondary systemic damage to multiple organs such as brain,heart,lung,liver and kidney.This paper provides a systematic review of the progress of research on acute poisoning with nitrobenzene in terms of its uses,causes,symptoms,histopathological changes,mechanism of poisoning and treatment,with a view to providing reference for the prevention,treatment and identification of nitrobenzene poisoning.

关 键 词：硝基苯 中毒 高铁血红蛋白血症 

分 类 号：TQ264.1[化学工程—有机化工] R556.65[医药卫生—血液循环系统疾病]