卵圆孔未闭因素对亲体肝移植术患儿围术期并发症及生存率的影响:回顾性研究  

Effect of patent foramen ovale on perioperative complications and survival rate in pediatric patients undergoing living donor liver transplantation:a retrospective study

作　　者：吴玉立[1] 翁亦齐[1] 井永乐 李天英 吴建江[4] 盛明薇[1] 贾莉莉[1] 刘伟华[1] 喻文立[1] Wu Yuli;Weng Yiqi;Jing Yongle;Li Tianying;Wu Jianjiang;Sheng Mingwei;Jia Lili;Liu Weihua;Yu Wenli(Department of Anesthesiology,Tianjin First Central Hospital,Tianjin 300192,China;Department of Cardiology,Tianjin First Central Hospital,Tianjin 300192,China;School of Medicine,Nankai University,Tianjin 300071,China;Department of Anesthesiology,First Affiliated Hospital of Xinjiang Medical University,Urumqi 830054,China)

机构地区：[1]天津市第一中心医院麻醉科,天津300192 [2]天津市第一中心医院心内科,天津300192 [3]南开大学医学院,天津300071 [4]新疆医科大学第一附属医院麻醉科,乌鲁木齐830054

出　　处：《中华麻醉学杂志》2023年第8期931-936,共6页Chinese Journal of Anesthesiology

基　　金：天津市卫生健康委员会科技项目(ZC20052);天津市医学重点学科(专科)建设项目(TJYXZDXK-045A);白求恩公益基金天津麻醉科研发展计划项目(TJMZ2022-005);新疆围术期器官保护实验室项目(2019D04019)。

摘　　要：目的:评价卵圆孔未闭(PFO)因素对亲体肝移植术患儿围术期并发症及生存率的影响。方法:回顾性收集2020年1月至2022年1月行亲体肝移植术的胆道闭锁患儿的病历资料,性别不限,年龄<18岁。根据术前超声心动图结果,将患儿分为PFO组和非PFO组。记录术中再灌注综合征、术后急性肺损伤、急性肾损伤和谵妄的发生情况以及1年生存情况。结果:与非PFO组比较,PFO组术中再灌注综合征、术后急性肺损伤、急性肾损伤和谵妄的发生率以及1年生存率差异无统计学意义( P>0.05)。 结论:PFO因素对亲体肝移植术患儿术中和术后早期并发症发生率及1年生存率无明显影响。Objective To evaluate the effect of patent foramen ovale(PFO)on the perioperative complications and survival rate in pediatric patients undergoing living donor liver transplantation.Methods The medical records from pediatric patients of either sex with biliary atresia,aged<18 yr,who underwent living donor liver transplantation from January 2020 to January 2022,were retrospectively collected.The pediatric patients were divided into PFO group and non-PFO group according to the results of echocardiography before operation.The postreperfusion syndrome,acute lung injury,acute kidney injury,postoperative delirium and 1-year survival rate were recorded.Results There was no significant difference in the incidence of postreperfusion syndrome,acute lung injury,acute kidney injury,postoperative delirium and one-year survival rate between PFO group and non-PFO group(P>0.05).Conclusions PFO has no obvious effect on the incidece of intraoperative and early postoperative complications and 1-year survival rate in pediatric patients undergoing living donor liver transplantation.

关 键 词：卵圆孔 未闭 儿童 肝移植 手术后并发症 存活率 

分 类 号：R726.5[医药卫生—儿科]