出 处:《四川中医》2023年第7期131-135,共5页Journal of Sichuan of Traditional Chinese Medicine
基 金:四川省中医药管理局中医药科研专项课题(课题编号:2021MS141)。
摘 要:目的:探究益气健脾活血法在老年髋部骨折围手术期并发胃肠功能紊乱中的预防价值。方法:选取2020年1月~2023年1月我院收治的老年髋部骨折患者224例,按照随机法将患者分为对照组、试验组,各112例。对照组患者行常规治疗,试验组患者在常规治疗基础上行辨证论治,使用益气健脾活血法进行治疗。分析两组患者治疗前后临床症状、凝血功能、炎症指标、胃肠功能指标、胃肠功能紊乱发生率以及不良反应发生率。结果:相较于对照组,试验组患者临床症状改善较好(P<0.05);治疗后相较于对照组,试验组PT、APTT上升幅度较大(P<0.05);治疗后两组患者炎症相关指标均有所下降,且与对照组相比,试验组SAA、TNG-α、IL-6水平均较低(P<0.05);治疗后两组患者胃肠功能相关指标均得到提升,且相较于对照组,试验组胃泌素、胃动素水平较高(P<0.05);服药前、服药3剂、服药6剂后对照组、试验组胃肠功能紊乱发生率相比,无差异性(P>0.05);停药4d后试验组胃肠功能紊乱发生率低于对照组(P<0.05);与对照组相比,试验组患者治疗后不良反应发生率略高(P>0.05)。结论:使用益气健脾活血法对行手术治疗老年髋部骨折手术患者进行治疗,能够有效改善患者凝血功能、炎症以及胃肠功能指标,有效的预防胃肠功能紊乱发生情况,起到较好的治疗效果。Objective:To explore the preventive value of Yiqi Jianpi Huoxue method in elderly patients with hip fracture complicated by gastrointestinal dysfunction during perioperative period.Methods:A total of 224elderly patients with hip fracture patients admitted to our hospital from April 2022to April 2023were selected,and the patients were randomly divided into control group and experimental group,with 112patients in each group.Patients in the control group were treated with conventional therapy,while the patients in the experimental group were treated with syndrome differentiation and treatment on the basis of conventional therapy,using the method of Yiqi Jianpi Huoxue method.Clinical symptoms,coagulation,inflammatory indicators,gastrointestinal function indicators,and the incidence of gastrointestinal disorders as well as the incidence of adverse effects were analyzed before and after treatment in both groups.Results:Compared with the control group,patients in the experimental group had a shorter time to the first flatus,time to the first defecation,and return of bowel sounds(P<0.05);After treatment,compared with the control group,Pt and APTT in the experimental group increased significantly(P<0.05);After treatment,the indexes related to inflammation decreased in both groups after treatment,and SAA,TNG in the experimental group were lower than those in the control group(P<0.05);After treatment,the related indexes of gastrointestinal function were improved in both groups,and the levels of gastrin and motilin were higher in the experimental group compared with the control group(P<0.05);There was no significant difference in the incidence of gastrointestinal dysfunction between the control group and the experimental group before,after 3and 6doses of medication(P>0.05);After 4days of drug withdrawal,the incidence of gastrointestinal dysfunction in the experimental group was lower than that in the control group(P<0.05);Compared with the control group,patients in the test group had a slightly higher incidence of posttreatm
关 键 词:益气健脾活血法 髋部骨折 胃肠功能紊乱 预防价值
分 类 号:R274.12[医药卫生—中医骨伤科学]
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