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作 者:郁烨 陈晋 周敏露 YU Ye;CHEN Jin;ZHOU Min-lu(General surgery department,Haion People's Hospitad,Haian Jiangsu 226600,China)
出 处:《四川中医》2023年第6期89-92,共4页Journal of Sichuan of Traditional Chinese Medicine
基 金:江苏省卫健委项目(编号:Z2019033,名称:载PTEN-BPV(pic)的神经干细胞联合壳聚糖支架在创伤性颅脑损伤后神经修复的研究)。
摘 要:目的:探讨浆细胞性乳腺炎(PCM)的磁共振成像(MRI)分型与中医证型的相关性。方法:回顾性选取2019年1月~2022年2月在本院收治的PCM患者96例(96处病灶)作为PCM组,根据中医证型的不同将患者分为肝经蕴热证组(n=57)、余毒未清证组(n=39)。记录所有患者的中医证候积分,并分析不同中医证型的MRI分型、表现及时间-信号强度曲线(TIC)、ADC值。结果:肝经蕴热证组以乳房结块、红肿、乳头凹陷为主,余毒未清证组以乳房肿胀溃疡、脓水淋漓及乳头凹陷为主。肝经蕴热证组ADC值显著低于余毒未清证组(P<0.05),但TIC比较无明显差异(P>0.05)。肝经蕴热证组MRI表现以脓肿型为主占75.44%(43/57),T1W1为低信号,T2W1为高信号,增强扫描为脓肿环形,片状或蜂窝状,其次为炎症型24.56%(14/57),未见混合型。余毒未清证组以脓肿型和混合型为主,分别占56.41%(22/39)和43.59%(17/39),未见炎症型。肝经蕴热证组和余毒未清证组MRI分型对比有显著差异(P<0.05)。结论:PCM的MRI分型与中医证型可能在疾病进展过程中逐渐趋于一致,临床可通过MRI检查为中医辨证论治提供参考。Objective:To explore the correlation between magnetic resonance imaging(MRI)classifications and TCM syn-dromes of plasma cell mastitis(PCM).Methods:A total of 96patients with PCM(96lesions)admitted to the hospital were retro-spectively enrolled as PCM group between January 2019and February 2022.According to dfferent TCM syndromes,they were di-vided into syndrome of dampness-heat of liver channel group(n=57)and syndrome of remained toxicity group(n=39).The scores of TCM syndromes were recorded.MRI classifications and manifestations,time-signal intensity curves(TIC)and ADC in patients with different TCM syndromes were analyzed.Results:The syndrome of dampness-heat of liver channel group was mainly characterized by breast lumps,swelling and nipples sinking,while syndrome of remained toxicity group was mainly characterized by breast swelling and ulcers,dripping pus and nipples sinking.ADC in syndrome of dampness-heat of liver channel group was significantly lower than that in syndrome of remained toxicity group(P<0.05),but there was no significant difference in TIC be-tween the two groups(P>0.05).In syndrome of dampness-heat of liver channel group,main MRI manifestations were abscess type[75.44%(43/57)],there was low signal on TIW1,high signal on T2W1,abscess ring-like,flake-like or honeycomb like enhancement scans,followed by inflammatory type[24.56%(14/57)],but there was no mixed type.In syndrome of re-mained toxicity group,main MRI manifestations were abscess type and mixed type[6.41%(22/39),43.59%(17/39)],but there was no inflammatory type.There were significant differences in MRI classifications between the two groups(P<0.05).Con-clusion:MRI classifications of PCM and TCM syndromes may gradually tend to be consistent in the process of disease progression.and the clinical examination of MRI may provide reference for TCM differential treatment.
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