胆黄润肠丸联合补中益气汤加减治疗气虚型老年功能性便秘的临床疗效观察  

Clinical observation of Danhuang Runchang pill combined with Buzhong Yiqi Decoction in the treatment of SenileFunctional Constipation with Qi deficiency

作　　者：殷燕[1] 李娜[1] YIN Yan;LI Na(Department of Spleen and Stomach Diseases,Changzhou Tra-ditional Chinese Medicine Hospital,Changchou Jiangsu 213000,China)

机构地区：[1]常州市中医医院脾胃病科,江苏常州213000

出　　处：《四川中医》2023年第6期137-140,共4页Journal of Sichuan of Traditional Chinese Medicine

摘　　要：目的:探究胆黄润肠丸联合补中益气汤加减治疗气虚型老年功能性便秘的临床疗效。方法:选取2020年1月到2021年8月常州市中医医院脾胃病科接诊的82例气虚型老年功能性便秘患者为研究对象。随机数字表法分为对照组(乳果糖口服液)和研究组(胆黄润肠丸联合补中益气汤加减治疗),各41例。统计治疗结束后的临床疗效。治疗前后采用便秘患者症状自评量表(PAC-SYM)对便秘症状进行评价。统计治疗前后的中医证候评分。统计治疗结束后1个月和3个月内的复发率。统计治疗期间恶心呕吐、腹泻、皮疹等不良反应的发生情况。结果:研究组的总有效率87.80%大于对照组的总有效率65.385%(P<0.05)。治疗后两组PAC-SYM得分低于治疗前,且研究组低于对照组(P<0.05)。治疗后,两组PAC-SYM评分和中医证候评分均低于治疗前,且研究组低于对照组(P<0.05)。研究组治疗后1个月和3个月的复发率低于对照组(P<0.05)。两组不良反应总发生率无统计学差异(P>0.05)。结论:胆黄润肠丸联合补中益气汤加减治疗气虚型老年功能性便秘的疗效确切,可缓解患者临床症状,降低复发率,且不良反应较低,值得临床推广使用。Objective To explore the clinical efficacy of Danhuang Runchang pill combined with Buzhong Yiqi Decoction in the treatment of qi deficiency elderly functional constipation.Methods From January 2020to August 2021,82elderly functional constipation patients with Qi deficiency in the Department of Spleen and Stomach Diseases of Changzhou Hospital of Traditional Chinese Medicine were selected as the research objects.The random number table method was used to divide into a control group(Lactulose oral liquid)and a study group(Danhuang Runchang pill combined with Buzhong Yiqi Decoction treatment),with 4lcases in each group.The clinical efficacy at the end of the treatment was counted.The constipation symptoms were evaluated before and after treatment by using the patient assessment of constipation symptom(PAC-SYM).The scores of TCM syndromes were calculated before and after treatment.The recurrence rate within Imonth and 3months after the end of treatment was counted.The occurrence of nausea,vomiting,diarrhea,rash and other adverse reactions during the treatment period were counted.Results The total effective rate of 87.80%in the study group was higher than 65.385%in the control group(P<0.05).After treatment,the PAC-SYM scores of both groups were lower than those before treatment,and the study group was lower than the control group(P<0.05).After treatment,the scores of TCM syndrome of the two groups were lower than those before treatment,and the study group were lower than the control group(P<0.05).The recurence rate of the study group was lower than that of the control group at lmonth and 3months after treatment(P<0.05).There was no significant difference in the total incidence of adverse reactions between the two groups(P>0.05).Conclusion:Danhuang Runchang pill combined with Buzhong Yiqi Decoction is effective in the treatment of elderly functional constipation with Qi deficiency.It can alleviate the clinical symptoms of patients,reduce the re-currence rate,and has low adverse reactions,which is worthy of clinical pro

关 键 词：胆黄润肠丸 补中益气汤 功能性便秘 老年 复发率 

分 类 号：R256.35[医药卫生—中医内科学]