健脾固肾方隔药灸治疗脾肾两虚型小儿遗尿临床疗效观察  

Clinical observation of Jianpi Gushen Decoction Separated Herbs-partition Moxibusition in children with pediatric enuresis of Spleen and Kidney Deficiency Type

作　　者：梁艳 田苗[1] 李红岩[2] LIANG Yan;TIAN Miao;UI Hongyan(Department of Pediatries,Baoding First Traditional Chinese Medicine Hospital,Baoding Hebei 071000,China;Department of Surgery,Baoding First Tradional Chinese Medicine Hospital,Baoding Hebei 071000,China)

机构地区：[1]保定市第一中医院儿科,河北保定071000 [2]保定市第一中医院外科,河北保定071000

出　　处：《四川中医》2023年第6期201-206,共6页Journal of Sichuan of Traditional Chinese Medicine

基　　金：保定市科技计划项目(编号:2141ZF103)。

摘　　要：目的:观察探讨健脾固肾方隔药灸治疗脾肾两虚型小儿遗尿症的临床疗效,总结临床治疗经验。方法:将保定市第一中医院儿科2018年6月~2021年6月收治的90例小儿遗尿症(脾肾两虚型)患儿作为研究对象,以随机数字表平均分为2组,各45例,对照组给予盐酸甲氯芬酯胶囊口服治疗,观察组在对照组基础上加用健脾固肾方隔药灸治疗,观察对比两组患儿治疗前和治疗1个月后的每周夜间遗尿次数、血浆抗利尿激素(ADH)、尿渗透压(Uosm)、睡眠质量(PSQI)评分、中医证候积分,并对比两组患儿治疗1个月后的临床疗效和观察两组治疗期间不良反应。结果:观察组患儿治疗1个月后夜间遗尿次数、Uosm1、Na^(+)、Cl^(-)浓度、PSQI各项评分均显著低于治疗前和对照组治疗后同期水平,AHD1、K^(+)、BUN浓度均显著高于治疗前和对照组治疗后同期水平,组内及组间比较均有统计学意义(P<0.05);观察组治疗1个月后疗效总有效率为95.6%,复发率为2.2%,对照组为73.3%,复发率为22.2%,组间比较均有统计学意义(P<0.05)。对照组不良反应发生率为13.3%,观察组不良反应发生率为8.9%,对比两组患儿的不良反应发生率无统计学意义(P>0.05)。结论:健脾固肾方隔药灸治疗脾肾两虚型小儿遗尿症的临床疗效显著,提高夜间ADH水平,降低夜间尿渗透压,减少小儿遗尿次数,明显改善患儿中医证候和睡眠质量,不良反应少,安全可靠,值得临床合理推广。Objective:To observe and explore the clinical effect of Jianpi Gushen Decoction separated herbs-partition moxi-busition on infantile enuresis of deficiency of pediatric enuresis of spleen and kidney deficiency type,and summarize the clinical treatment experience.Methods:90children with infantile enuresis(Spleen and Kidney Deficiency Type)treated in pediatrics of the first hospital of traditional Chinese medicine in Baoding from June 2018to June 2021were randomly divided into two groups with 45cases in each group.The control group was treated with oral meclofenac hydrochloride capsule,and the observation group was treated with separated herbs-partition moxibusition of Jianpi Gushen decocotion on the basis of the control group,The fre-quency of nocturnal enuresis,plasma antidiuretic hormone(ADH),urinary osmolality(uosm),sleep quality(PSQI)score and TCM syndrome score of the two groups before and 1month after treatment were observed and compared.The clinical efficacy and adverse reactions of the two groups after Imonth of treatment were compared.Results:After one month of treatment,the number of nocturnal enuresis,the concentration of uosml,Na^(+),Cl^(-)and the scores of PSQ in the observation group were significantly lower than those before treatment and in the control group,and the concentrations of ahdl,K^(+),bun were significantly higher than those before treatment and in the control group(P<0.05);After one month of treatment,the total effective rate of the observation group was 95.6%,the recurrencerate was 2.2%,the control group was 73.3%,and the recurrence rate was 22.2%.There was significant diference between the groups(P<0.05).The incidence of adverse reactions was 13.3%in the control group and 8.9%in the observation group.There was no significant dfference in the incidence of adverse reactions between the two groups(χ^(2)=0.11,P>0.05).Conclusion:Jianpi Gushen decoction separated herbs-partition moxibusition has a significant clinical effect in the treatment of infantile enuresis with spleen and kidney defi

关 键 词：健脾固肾方 隔药灸 脾肾两虚型 小儿遗尿症 睡眠质量 

分 类 号：R245.82[医药卫生—针灸推拿学]