甘肃省少数民族地区儿童氟斑牙患病情况及危险因素  

Prevalence and risk factors of dental fluorosis among children from minority areas of Gansu Province

作　　者：吕程程 陈晓燕[2] 张婕 张勇 杨琳 闫娟 刘艳丽 张本忠[1] LYU Chengcheng;CHEN Xiaoyan;ZHANG Jie;ZHANG Yong;YANG Lin;YAN Juan;LIU Yanli;ZHANG Benzhong(Institute of Occupational Hygiene and Environmental Hygiene,School of Public Health,Lanzhou University,Lanzhou 730030,China;Department of Endemic Disease Control,Gansu Provincial Center for Disease Control and Prevention,Lanzhou 730030,China;Department of Disease Control and Prevention,Xining Municipal Health Commission,Xining 810003,China)

机构地区：[1]兰州大学公共卫生学院劳动卫生与环境卫生研究所,兰州730030 [2]甘肃省疾病预防控制中心地方病防制科,兰州730030 [3]西宁市卫生健康委员会疾病预防控制科,西宁810003

出　　处：《中华疾病控制杂志》2023年第9期1025-1029,1058,共6页Chinese Journal of Disease Control & Prevention

基　　金：甘肃省中医药科研课题(GZKP-2020-27)。

摘　　要：目的了解甘肃省少数民族地区儿童氟斑牙的患病情况,探讨氟斑牙发病的危险因素。方法于2019年6―11月采用分层整群随机抽样方法,对甘肃省8个少数民族县的1344名在校学生进行资料收集、氟斑牙诊断和尿样中氟化物检测。结果甘肃省少数民族地区8~12岁儿童氟斑牙患病率为29.1%,尿氟浓度几何均值为1.02 mg/L。居住在阿克塞哈萨克族自治县(阿克塞县)(OR=2.625,95%CI:1.530~4.597,P=0.001)、肃南裕固族自治县(肃南县)(OR=2.421,95%CI:1.411~4.154,P=0.001)、天祝藏族自治县(天祝县)(OR=2.813,95%CI:1.599~4.946,P<0.001)和夏河县(OR=1.719,95%CI:1.022~2.892,P=0.041)、具有饮茶习惯(OR=1.508,95%CI:1.072~2.120,P=0.018)、年龄较大(8~12岁)(OR=1.122,95%CI:1.021~1.233,P=0.017)、尿氟浓度较高(0.10~5.87 mg/L)(OR=1.549,95%CI:1.223~1.962,P<0.001)是影响儿童氟斑牙患病率的危险因素。结论甘肃省少数民族地区儿童氟斑牙患病率较高,地区、饮茶习惯、年龄、尿氟等因素均会影响氟斑牙患病率,应针对性地开展饮茶型地氟病持续性防制工作。Objective This study seeks to understand the prevalence of dental fluorosis in children residing in ethnic minority areas of Gansu Province and to explore the risk factors of dental fluorosis.Methods Between June and November 2019,1344 students from eight ethnic minority counties in Gansu Province were included using the stratified cluster random sampling method.These participants underwent data collection,dental fluorosis diagnosis and fluoride detection in urine samples.Results The prevalence of dental fluorosis among children aged 8-12 years in minority areas of Gansu Province was 29.1%,with a geometric mean urinary fluoride concentration of 1.02 mg/L.Living in the areas of Aksai(OR=2.625,95%CI:1.530-4.597,P=0.001),Sunan(OR=2.421,95%CI:1.411-4.154,P=0.001),Tianzhu(OR=2.813,95%CI:1.599-4.946,P<0.001)and Xiahe(OR=1.719,95%CI:1.022-2.892,P=0.041)counties,having tea-drinking habits(OR=1.508,95%CI:1.072-2.120,P=0.018),older age(8-12 years old)(OR=1.122,95%CI:1.021-1.233,P=0.017)and high urinary fluoride concentration(0.10-5.87 mg/L)(OR=1.549,95%CI:1.223-1.962,P<0.001)were risk factors affecting the prevalence of dental fluorosis in children.Conclusions The prevalence of dental fluorosis among children is high in ethnic minority areas of Gansu Province.The factors such as region,tea-drinking habits,age,and urinary fluoride can affect the prevalence of dental fluorosis.Continuous prevention and treatment of tea-drinking type dental fluorosis should be carried out in a targeted manner.

关 键 词：氟斑牙 尿氟 氟中毒 危险因素 

分 类 号：R181[医药卫生—流行病学]