超声造影与高分辨率CT鉴别诊断周围型肺肿物良恶性的价值分析  

Value Analysis of CEUS and High-resolution CT in the Differential Diagnosis of Benign and Malignant Peripheral Lung Mass

作　　者：孙春娟[1] 蒋晓娟[1] 张晴[1] 王珏 SUN Chun-juan;JIANG Xiao-juan;ZHANG Qing;WANG Jue(Ultrasonography Department,Nantong Cancer Hospital,Jiangsu 226361,China)

机构地区：[1]南通市肿瘤医院超声科,江苏226361

出　　处：《影像技术》2023年第5期66-70,共5页Image Technology

摘　　要：目的:研究超声造影(CEUS)、高分辨率CT(HRCT)在周围型肺肿物良恶性鉴别诊断中的应用价值。方法:选取南通市肿瘤医院在2019年8月至2023年6月收治的周围型肺肿瘤患者90例为对象,以病理结果为诊断金标准,根据肺肿物的良恶性将患者分成良性组和恶性组,均进行超声造影检查和高分辨率CT检查,计算两种影像学方法对肺肿物良恶性鉴别诊断的准确率、灵敏度和特异度,对比良恶性组的CEUS定量参数以及HRCT各种征象的检出率等。结果:CEUS、HRCT在周围型肺肿物良恶性的鉴别诊断准确率、灵敏度和特异度对比差异均不显著(P>0.05);在CEUS的定量参数方面,良性组与恶性组在TIC曲线的各参数比较差异不显著(P>0.05),良性组的AT1、AT2和△AT均明显早于恶性组(P<0.05);在HRCT检查的征象检出率上,良性组的分叶征、钙化、毛刺征和胸膜凹陷征的检出率均低于恶性组(P<0.05),空泡征的检出率良恶性组之间差异不显著(P>0.05);经ROC曲线分析,CEUS、HRCT、CEUS联合HRCT的AUC值分别为0.823、0.840、0.895。结论:CEUS与HRCT在周围型肺肿物良恶性鉴别诊断中应用价值均较高,二者联合应用能提高鉴别诊断价值,必要时可联合应用,以准确鉴别诊断肺肿物的良恶性,指导临床治疗。Objective:To investigate the application value of contrast-enhanced ultrasound(CEUS)and high-resolution CT(HRCT)in the differential diagnosis of benign and malignant peripheral lung mass.Methods:90 patients with peripheral lung tumors admitted to Nantong cancer hospital from August2019 to June 2023 were selected as reseach objects.Taking the pathological results as the gold standard for diagnosis,patients were divided into benign and malignant group,according to the benign and malignant nature of lung mass.(CEUS)and HRCT examination were performed,and the accuracy,sensitivity and specificity of the two imaging methods for the differential diagnosis of lung mass benign and malignant were calculated.and compared the quantitative parameters of CEUS and detection rate of various signs of HRCT in the benign and malignant group.Results:The differences in the differential diagnostic accuracy,sensitivity and specificity of CEUS and HRCT in the benign and malignant peripheral lung mass were not significant(P>0.05),and in terms of the quantitative parameters of CEUS,the difference in the parameters of the TIC curve between benign group and malignant group were not significangt(P>0.05).However,AT1,AT2 and△AT in the benign group were significantly earlier than those in the malignant group(P<0.05),and in terms of the detection rate of the HRCT examination,the detection rate of leaf segmentation sign,calcification,burr sign and pleural depression sign in the benign group were lower than those in the malignant group(P<0.05),while the detection rate of vacuolar sign was not significant between benign and malignant groups(P 0>.05).After the ROC curve analysis,the AUC values of CEUS,HRCT,and CEUS combined with HRCT were 0.823,0.840,and 0.895,respectively.Conclusion:CEUS and HRCT have high application value in the differential diagnosis of benign and malignant peripheral lung masses.The combination of the two method can improve the differential diagnosis value,and if necessary,it can be combined to accurately identify the benign

关 键 词：周围型肺肿物 良恶性 高分辨率CT 超声造影 

分 类 号：R445.1[医药卫生—影像医学与核医学]