牛结节性皮肤病研究进展  

Progress in researches on lumpy skin diseases in cattle

作　　者：程肖晔 王晓亮 常广军[1] 左冉坤 沈向真[1] 李知新 CHENG Xiaoye;WANG Xiaoliang;CHANG Guangjun;ZUO Rankun;SHEN Xiangzhen;LI Zhixin(College of Veterinary Medicine,Nanjing Agriculture University,Nanjing 210095,China;Ningxia Animal Center for Animal Disease Prevention and Control,Yinchuan 750000,China)

机构地区：[1]南京农业大学动物医学院,江苏南京210095 [2]宁夏动物疾病预防控制中心,宁夏银川750000

出　　处：《畜牧与兽医》2023年第9期144-150,共7页Animal Husbandry & Veterinary Medicine

基　　金：宁夏重点研发项目——黄河生态流域生态环境保护与高质量发展科技支撑专项(21BEF02019)。

摘　　要：牛结节性皮肤病(LSD)是一种病毒性疾病,主要的易感动物是牛,具有高度的传染性,会对地方经济产生重大影响,被我国暂定为二类动物疫病。牛结节性皮肤病病毒(LSDV)、山羊痘病毒(GTPV)与绵羊痘病毒(SPPV)都属于痘病毒科下脊索动物痘病毒亚科中的山羊痘病毒属。为开发有效的诊断试剂和疫苗,以及理解病毒发病机制和流行病学情况,深入了解病毒的分子特征非常重要。本文综述了牛结节性皮肤病的现状,包括其病原学特征、临床症状、基因组功能、流行病学以及对牛生产的影响,并探讨了实验室诊断、疫苗的最新进展以及未来的防控方向。Lumpy skin disease(LSD)is a viral disease,to which the major animal susceptible is cattle.The disease is highly infectious and exerts a significant impact on the local economy.Therefore,it is tentatively designated as a second-class animal disease in China.Lumpy skin disease virus(LSDV),goatpox virus(GTPV)and sheeppox virus(SPPV)all belong to the genus of Capripoxvirus,of the subfamily of Chordopoxvirinae,and of family of Poxviridae.In order to develop more effective diagnostic reagents and vaccines,and to understand the pathogenesis and epidemiological mechanisms of the viruses,it is of great importance for us understand their molecular characteristics.This article briefly summarizes what is known about lumpy skin diseases,including their etiological characteristics,genome function,impact on livestock production,epidemiology,clinical symptoms,discusses recent advances in research on related diagnostic tests and vaccine developments,and looks into future direction in prevention and control of the diseases.

关 键 词：牛结节性皮肤病 病毒特征 流行病学 临床症状 实验室诊断 疫苗 

分 类 号：S855.3[农业科学—临床兽医学]