A 24 hour naproxen dose on gastrointestinal distress and performance during cycling in the heat  

作　　者：Dawn M.Emerson J.Mark Davis Stephen CL.Chen Toni M.Torres-McGehee Craig E.Pfeifer Charles C.Emerson Joseph D.Bivona Justin V.Stone 

机构地区：[1]Department of Health,Sport,and Exercise Sciences,University of Kansas,Lawrence,Kansas,USA [2]Department of Exercise Science,University of South Carolina,Columbia,SC,USA [3]Division of Exercise and Sport Science,Bob Jones University,Greenville,South Carolina,USA [4]Applied Sport and Exercise Sciences,The Park,University of Gloucestershire,Cheltenham GL502RH,United Kingdom [5]Department of Athletics,University of Missouri-Kansas City,Kansas City,USA

出　　处：《Sports Medicine and Health Science》2020年第1期19-24,共6页运动医学与健康科学（英文）

摘　　要：Using a double-blind,randomized and counterbalanced,cross-over design,we assessed naproxen's effects on gastrointestinal(GI)distress and performance in eleven volunteers(6 male,5 female).Participants completed 4 trials:1)placebo and ambient);2)placebo and heat;3)naproxen and ambient;and 4)naproxen and heat.Independent variables were one placebo or 220 mg naproxen pill every 8 h(h)for 24 h and ambient(22.7±1.8℃)or thermal environment(35.7±1.3℃).Participants cycled 80 min at a steady heart rate then 10 min for maximum distance.Perceived exertion was measured throughout cycling.Gastrointestinal distress was assessed pre-,during,post-,3 h post-,and 24 h post-cycling using a GI index for upper,lower,and systemic symptoms.No statistically significant differences occurred between conditions at any time for GI symptoms or perceived exertion,distance,or heart rate during maximum effort.A 24 h naproxen dose did not significantly affect performance or cause more frequent or serious GI distress when participants were euhydrated and cycling at moderate intensity in a thermal environment.

关 键 词：NSAID Gastrointestinal bleeding Heart rate Perceived exertion 

分 类 号：TG1[金属学及工艺—金属学]