高频呼吸机在新生儿重症急性呼吸衰竭中的应用价值  

Application Value of High Frequency Ventilator in Neonatal Severe Acute Respiratory Failure

作　　者：贺元成 刘静 敖小冬 HE Yuancheng;LIU Jing;AO Xiaodong(Maternity&Child Care Center of Xinyu,Jiangxi Province,Xinyu 338025,China;不详)

机构地区：[1]江西省新余市妇幼保健院,江西新余338025

出　　处：《中国医学创新》2023年第28期14-17,共4页Medical Innovation of China

基　　金：新余市指导性科技计划项目(20223090977)。

摘　　要：目的:探讨高频呼吸机在新生儿重症急性呼吸衰竭中的应用价值。方法:回顾性分析新余市妇幼保健院2020年8月—2022年11月收治的60例重症急性呼吸衰竭新生儿的临床资料,将采用常频呼吸机治疗的30例设为对照组,采用高频呼吸机治疗的30例设为观察组。比较两组血气分析指标、呼吸机应用情况、生命体征指标、存活率及并发症。结果:治疗后,观察组动脉血氧分压(PaO_(2))、氧合指数(OI)分别为(72.86±6.25)、(217.63±21.25)mmHg,均高于对照组的(67.47±6.12)、(198.76±19.32)mmHg,动脉血二氧化碳分压(PaCO_(2))为(45.23±4.28)mmHg,低于对照组的(50.31±5.13)mmHg,差异均有统计学意义(P<0.05)。观察组通气总持续时间、撤机后总给氧时间分别为(71.82±6.69)、(47.85±5.13)h均短于对照组的(82.52±7.47)、(54.59±5.48)h,差异均有统计学意义(P<0.05)。治疗后,观察组平均动脉压(MAP)为(50.59±4.25)mm Hg,高于对照组的(46.55±4.21)mm Hg,心率(HR)、呼吸频率(RR)分别为(130.41±8.96)、(41.52±4.15)次/min均低于对照组的(135.52±9.12)、(45.89±4.23)次/min,差异均有统计学意义(P<0.05);两组存活率、并发症相比,差异均无统计学意义(P>0.05)。结论:高频呼吸机在新生儿重症急性呼吸衰竭中应用效果良好,可更好改善血气分析指标,稳定生命体征,缩短呼吸机使用时间,值得临床广泛应用。Objective:To explore the application value of high frequency ventilator in neonatal severe acute respiratory failure.Method:The clinical data of 60 newborns with severe respiratory failure admitted to Maternity&Child Care Center of Xinyu from August 2020 to November 2022 were retrospectively analyzed.30 cases treated with constant frequency ventilator were set as the control group,and 30 cases treated with high frequency ventilator were set as the observation group.The blood gas analysis index,ventilator application,vital sign index,survival rate and complications were compared between the two groups.Result:After treatment,the arterial partial oxygen pressure(PaO_(2))and oxygenation index(OI)in the observation group were(72.86±6.25)and(217.63±21.25)mmHg were higher than(67.47±6.12)and(198.76±19.32)mmHg in the control group,arterial partial pressure in carbon dioxide(PaCO_(2))was(45.23±4.28)mmHg was lower than(50.31±5.13)mmHg in control group,the differences were statistically significant(P<0.05).The total duration of ventilation and the total oxygen administration time after weaning in the observation group were(71.82±6.69)and(47.85±5.13)h,which were shorter than(82.52±7.47)and(54.59±5.48)h in the control group,the differences were statistically significant(P<0.05);after treatment,the mean arterial pressure(MAP)of the observation group was(50.59±2.25)mmHg,higher than(46.55±2.21)mmHg of the control group,the heart rate(HR)and respiratory rate(RR)were(130.41±8.96),(41.52±4.15)times/min,lower than(135.52±9.12),(45.89±4.23)times/min of the control group,the differences were statistically significant(P<0.05);there were no significant differences in survival rate and complications between the two groups(P>0.05).Conclusion:The application of high frequency ventilator in neonatal severe acute respiratory failure is effective,which can better improve blood gas analysis index,stabilize vital signs,shorten the use time of ventilator,and is worthy of wide clinical application.

关 键 词：新生儿重症急性呼吸衰竭 高频呼吸机 常频呼吸机 血气分析 

分 类 号：R722.1[医药卫生—儿科]