Analysis of the distribution characteristics of enterovirus types based on environmental surveillance from 2013 to 2021 in Fujian Province, China  

作　　者：Xiuhui Yang Shaojian Cai Xiaoqian Wu Yong Zhang Dong Li Yahong Chen Qianjing Chen Shuangli Zhu Dongmei Yan Wenbo Xu Hairong Zhang Zhifei Chen Suhan Zhang Yong Zhou Mengping Zhang Ningxuan Zheng Na You 

机构地区：[1]Fujian Province Key Laboratory of Zoonosis Research,Fujian Center for Disease Control and Prevention,Fuzhou 350012,China [2]School of Basic Medical Sciences,Fujian Medical University,Fuzhou 350108,China [3]WHO WPRO Regional Polio Reference Laboratory and Ministry of Health Key Laboratory for Medical Virology,National Institute for Viral Disease Control and Prevention,Chinese Center for Disease Control and Prevention,Changping District,Beijing 102206,China [4]Quanzhou Center for Disease Control and Prevention,Quanzhou 362018,China [5]Longyan Center for Disease Control and Prevention,Longyan 364000,China [6]Public Health School of Fujian Medical University,Fuzhou 350108,China

出　　处：《Biosafety and Health》2023年第4期240-249,共10页生物安全与健康（英文）

基　　金：funded by Fujian Health System Youth Backbone Talents training project(2013-ZQN-ZD-10);leading(key)project of social development in Fujian Province(2017Y0011);National Key Research and Development Program of China(2021YFC2302003)。

摘　　要：Environmental surveillance (ES) is a useful approach for monitoring circulating viruses, including polioviruses (PVs) and non-polio enteroviruses (NPEVs). In this study, the results of nine years of ES from 2013 to 2021 at six sampling sites in three cities in Fujian Province, China, were summarized. It showed that the sewage samples contained abundant viruses, but the positive rate was affected by different sampling sites. From the 520 samples, 431 PVs, 1,713 NPEVs, and 281 human adenoviruses (HAdVs) were isolated. PV isolates had been markedly affected following the adjustment of the immunization strategy. All but one PV isolate were Sabin-like strains without wild PVs. One isolate was vaccine-derived PV type 3 with 10 variation points in theVP1 region. After May 2016, PV type 2 was no longer detected, and PV type 3 became a superior serotype. Of 1,713 NPEVs, 24 serotypes were identified, including echovirus11 (E11), E6, coxsackievirus B3 (CVB3), CVB5, E7, and E3 were the predominant serotypes (37.65%, 20.96%, 11.50%, 8.87%, 8.23%, and 7.06%, respectively). The temporal dynamic of the six common serotypes was inconsistent. E3 was frequently isolated, but the number of isolates was low, with no obvious peaks. E6, E7, and CVB3 exhibited periodic changes with a high peak every three to four years, and E11 only had one high peak lasting four years. Summer-fall peaks of the echoviruses and spring-winter peaks of CVB were observed in the monthly distribution of virus isolation. The infectious isolates of various serotypes of different species identified from the sewage samples showed that ES is an essential part of pathogen surveillance.

关 键 词：Enterovirus surveillance Enteroviruse POLIOVIRUS Distribution characteristics 

分 类 号：R373[医药卫生—病原生物学]