An optical tweezer-based microdroplet imaging technology  

作　　者：Cong Zhai Yujian Hong Zuzeng Lin Yulu Chen Han Wang Tong Guo Chunguang Hu 

机构地区：[1]State Key Laboratory of Precision Measuring Technology and Instruments,Tianjin University,Tianjin 300072,China

出　　处：《Nanotechnology and Precision Engineering》2023年第3期27-33,共7页纳米技术与精密工程（英文）

基　　金：supported by the National Natural Science Foundation of China(Grant Nos.52075383 and 61927808).

摘　　要：Microspheres can break the diffraction limit and magnify nano-structure imaging,and with its advantages of low cost and label-free operation,microsphere-assisted imaging has become an irreplaceable tool in the life sciences and for precision measurements.However,the tiny size and limited imaging field of traditional solid microspheres cause difficulties when imaging large sample areas.Alternatively,droplets have similar properties to those of microspheres,with large surface curvature and refractive-index difference from the surrounding environment,and they can also serve as lenses to focus light for observation and imaging.Previous work has shown that droplets with controllable size can be generated using an optical tweezer system and can be driven by optical traps to move precisely like solid microspheres.Here,a novel microdroplet-assisted imaging technology based on optical tweezers is proposed that better integrates the generation,manipulation,and utilization of droplets.

关 键 词：Optical tweezers Photogenerated droplets Assisted imaging Controllable generation 

分 类 号：TH74[机械工程—光学工程]