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机构地区:[1]CAS Key Laboratory of Infection and Immunity,Institute of Biophysics,Chinese Academy of Sciences,Beijing 100101,China [2]University of Chinese Academy of Sciences,Beijing 100049,China [3]CAS Center for Excellence in Biomacromolecules,Institute of Biophysics,Chinese Academy of Sciences,Beijing 100101,China
出 处:《Journal of Molecular Cell Biology》2023年第2期1-2,共2页分子细胞生物学报(英文版)
摘 要:As intracellular parasites,viruses must modulate the environment of host cells to facilitate viral genome replication and virion assembly.One strategy is to establish specialized,membrane-associated subcellular structures to concentrate viral and cellular components and mediate viral replication processes.This strategy is utilized by many positive-strand RNA viruses such as coronaviruses,hepatitis C virus,and Zika virus,and they re-organize host endo-membranes to form double-membrane vesicles for viral genome replication(Wolff et al.,2020).
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