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作 者:蓝卡尔 刘宇阳 吴诗怡 殷晓浦[1,2] 卫秋慧 LAN Kaer;LIU Yuyang;WU Shiyi;YIN Xiaopu;WEI Qiuhui(College of Pharmacy,Hangzhou Normal University,Hangzhou 311100,China;Key Laboratory of Elemene Class Anti-Cancer Chinese Medicines of Zhejiang Provice,Engineering Laboratory of Development and Application of Traditional Chinese Medicines from Zhejiang Provice,Collaborative Innovation Center of Traditional Chinese Medicines of Zhejiang Province,Hangzhou 311100,China)
机构地区:[1]杭州师范大学药学院,杭州311100 [2]浙江省榄香烯类抗癌中药研究重点实验室,浙产中药材资源开发与应用浙江省工程实验室,浙江省中药协同创新中心,杭州311100
出 处:《植物生理学报》2023年第9期1709-1719,共11页Plant Physiology Journal
基 金:国家自然科学基金(81903742);浙江省自然科学基金(LQ19C020002)。
摘 要:萜类化合物是天然产物中数量最多的一类,广泛应用于医药、食品、化妆品等多个领域。MYB家族是植物最大的转录因子家族之一,在植物次生代谢调控方面起着重要作用。本文总结了MYB转录因子参与植物萜类生物合成调控的研究。MYB不仅直接调控萜类合成途径酶基因的表达,还可以与其他转录因子协同或拮抗调控萜类生物合成。此外,MYB蛋白介导光、激素、低磷等环境诱导的萜类合成调控。通过深入探讨MYB调控萜类合成的机制,旨在为进一步研究萜类生物合成调控奠定基础。Terpenoids are the most abundant natural products,which are widely used in various fields such as medicine,food,and cosmetics.MYB family is one of the largest transcription factor families,playing an important role in the regulation of secondary metabolism in plants.In this study,we reviewed the research-es of MYB transcription factors in the regulation of terpenoids biosynthesis in plants.MYB not only directly regulates the expression of enzyme genes in the terpenoid biosynthesis pathway,but also cooperates or antagonizes with other transcription factors to regulate terpenoid biosynthesis.In addition,MYB proteins mediate the regulation of terpenoid biosynthesis induced by light,hormones,low phosphate,etc.In-depth exploration of the transcriptional regulation mechanism of MYB is aimed to lay a foundation for further re-search on terpenoid biosynthesis regulation.
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