聚烯丙胺改性磺酸催化剂催化苯甲酸正丁酯的合成  

Polyallylamine Modified Sulfonic Acid Catalyst Catalyse Synthesis of n-Butyl Benzoate

作　　者：于亚洲 赵先亮[1] 谭宁宁 肖洋 张拥军 YU Ya-Zhou;ZHAO Xian-Liang;TAN Ning-Ning;XIAO Yang;ZHANG Yong-Jun(School of Biological and Chemical Engineering,Zhejiang University of Science and Technology,Hangzhou 310023,China;Zhejiang Wild Wind Pharmaceutical Co.Ltd.,Dongyang 322100,China)

机构地区：[1]浙江科技学院生物与化学工程学院,杭州310023 [2]浙江野风药业有限公司,东阳322100

出　　处：《应用化学》2023年第10期1430-1436,共7页Chinese Journal of Applied Chemistry

摘　　要：发展聚合物载体催化剂是有效解决催化剂利用及绿色合成化学的重要课题。烯丙胺盐酸盐作为单体在引发剂作用下聚合得到聚烯丙胺,通过环氧氯丙烷进行交联得到交联的聚烯丙胺盐酸盐。以交联聚烯丙胺作为载体,通过与氯磺酸反应,制备了高负载的固体磺酸催化剂。交联聚烯丙胺磺酸催化剂在150℃以内均是稳定的,表现出良好的热稳定性。该催化剂被用于催化苯甲酸与正丁醇反应制备苯甲酸正丁酯。反应的最佳条件为丁醇与苯甲酸(BA)的摩尔比为2∶1,催化剂用量为20 g/mol BA,反应温度为120℃,反应时间为6 h;苯甲酸的酯化率为95%。该催化剂可以重复利用多达4次而保持较高的催化性能。Developing polymer carrier catalysts is an important topic for effectively addressing catalyst utilization and green synthetic chemistry.As a monomer,allylamine hydrochloride is polymerized with initiation to obtain polyallylamine which is cross-linked with epichlorohydrin to obtain cross-linked polyallylamine hydrochloride.Using cross-linked polyallylamine as a carrier,a solid acid catalyst with high loading is prepared by reacting with chlorosulfonic acid.The cross-linked polyallylamine sulfonic acid catalyst is stable up to 150℃,indicating its excellent thermal stability.This catalyst is used to catalyze the reaction of benzoic acid and n-butanol to produce n-butyl benzoate.The optimal reaction conditions are:the molar ratio of n-butanol to benzoic acid of 2∶1,the catalyst dosage of 20 g/mol BA,reaction temperature of 120℃ and reaction time of 6 h.The esterification rate of benzoic acid is 95%.This catalyst can be reused up to 4 times while maintaining high catalytic performance.

关 键 词：聚合物载体 聚烯丙胺 磺酸 苯甲酸正丁酯 

分 类 号：O643.3[理学—物理化学] TQ225.2[理学—化学]