姜黄素高热环境下器官保护作用的研究进展  

Research progress on protective effect of curcumin on organs under high temperature environment

作　　者：阿文丽 张衡頔 胡吉蕾 肖春秀 凡蝶 康超 时皎皎 林宁 A Wen-li;ZHANG Heng-di;HU Ji-lei;XIAO Chun-xiu;FAN Die;KANG Chao;SHI Jiao-jiao;LIN Ning(Department of Nutrition,The General Hospital of Western Theater Command,Chengdu 610083,China;The 941st Hospital of Joint Logistics Support Force of the People's Liberation Army,Xining 810000,China;Department of Ophthalmology,The General Hospital of Western Theater Command,Chengdu 610083,China)

机构地区：[1]中国人民解放军西部战区总医院营养科,四川成都610083 [2]中国人民解放军联勤保障部队第941医院,青海西宁810000 [3]中国人民解放军西部战区总医院眼科,四川成都610083

出　　处：《现代药物与临床》2023年第9期2362-2367,共6页Drugs & Clinic

基　　金：四川省自然科学基金资助项目(2022NSFSC1422);四川省中医药管理局科学技术研究专项课题(2021MS536);四川省中医药管理局科学技术研究专项课题(2021MS422)。

摘　　要：高热环境下水、电解质流失严重,机体散热功能下降,可引起一系列热应激产生的损伤性疾病,严重威胁着急性进入和需长期在高热环境中工作的人员的身心健康和工作能力。姜黄素是亲脂类多酚化合物,是姜黄中的主要有效成分,具有广泛的药理作用。姜黄素在高热环境下对各类器官发挥保护作用,如心血管、肺和气道、骨骼肌、肝脏、肾脏、胃肠道等。总结了在高热环境下姜黄素对器官的保护作用,为姜黄素防治热应激产生的损伤性疾病提供参考。Objective:The loss of water and electrolyte in high temperature environment is serious,and the heat dissipation function of the body reduces,which can cause a series of damage diseases caused by heat stress,and it seriously threatens the physical and mental health and work ability of personnel who have acute entry and need to work in high heat environments for a long time.Curcumin is a lipophilic polyphenolic compound,which is the main active ingredient extracted from Curcumae Longae Rhizoma,and has a wide range of pharmacological effects.Curcumin could play a protective role in organs in a high fever environment,such as cardiovascular,lung and airway,skeletal muscle,liver,kidney,and gastrointestinal tract,etc.This paper summarizes the protective effect of curcumin on organs in high heat environments,so as to provide reference for the prevention and treatment of heat stress-induced injury diseases with curcumin.

关 键 词：姜黄素 高热 心血管 肺和气道 骨骼肌 肝脏 肾脏 胃肠道 保护作用 

分 类 号：R285.5[医药卫生—中药学] R977[医药卫生—中医学]