清热利湿汤协同抗生素治疗盆腔炎性疾病湿热瘀结证的临床研究  

Clinical study of Qingrelishi decoction combined with antibiotics for treating pelvic inflammatory disease wity dampness-heat stasis syndrome

作　　者：矫楷琼 滕秀香[2] JIAO Kaiqiong;TENG Xiuxiang(Yanqing Hospital of Beijing Hospital of Traditional Chinese Medicine,Beijing,102100;Beijing Hospital of Traditional Chinese Medicine affiliated to Capital Medical University)

机构地区：[1]北京中医医院延庆医院,102100 [2]首都医科大学附属北京中医医院

出　　处：《中国计划生育学杂志》2023年第10期2447-2451,共5页Chinese Journal of Family Planning

基　　金：首都卫生发展科研专项(首发2022-2-2233)。

摘　　要：目的:评价清热利湿汤协同抗生素治疗盆腔炎性疾病(PID)湿热瘀结证的临床疗效。方法:65例PID湿热瘀结证患者,随机分为观察组(32例)、对照组(33例),两组均予甲磺酸左氧氟沙星片联合甲硝唑维B6片口服,观察组同时予清热利湿汤中药饮片口服,两组均治疗2周,观察治疗效果。结果:治疗第1、2周后,观察组盆腔痛体征积分改善均优于对照组(P<0.05)。治疗2周后,观察组中医证候积分总分改善优于对照组(P<0.05);观察组有效率为93.9%,优于对照组的75.0%(P<0.05)。治疗第3,7天,观察组白细胞计数、中性粒细胞百分比均低于对照组(P<0.05);治疗第3天,观察组C反应蛋白水平低于对照组(P<0.05)。结论:清热利湿汤协同抗生素治疗PID湿热瘀结证临床有效,值得应用。Objective:To evaluate the clinical effect of Qingrelishi decoction combined with antibiotics for treating the dampness-heat stasis syndrome caused by pelvic inflammatory disease(PID) of patients.Methods:A total of 65 patients with dampness-heat stasis syndrome caused by PID were selected and were randomly divided into experimental group(n=32) and control group(n=33).The patients in both groups were treated with the tablets of levofloxacin mesylate combined with metronidazole vitamin B6 for two weeks.The patients in the experimental group were given the Qingrelishi decoction additionally during the same time.The therapeutic effect of the patients in the two groups was observed.Results:The improvement of pelvic pain sign scores of the patients in the experimental group after 1 week and 2 weeks of the treatment was significantly better than that of the patients in the control group(P<0.05).The improvement of total score of TCM syndrome of the patients in the experimental group after 2 weeks of treatment was significantly better than that of the patients in the control group(P<0.05).The effective rate of the patients in the experimental group was 93.9%,which was significantly better than that(75.0%) of the patients in the control group(P<0.05).The leukocyte count and the neutrophil percentage of the patients in the experimental group on the 3rd and 7th day of treatment were significantly lower than those of the patients in the control group(P<0.05).The C-reactive protein level of the patients in the experimental group on the 3rd day of treatment was significantly lower than that of the patients in the control group(P<0.05).Conclusion:Qingrelishi decoction combined with antibiotic treatment for PID of the patients is effective,and which is worthy of application.

关 键 词：盆腔炎性疾病 湿热瘀结 清热利湿汤 

分 类 号：R711.3[医药卫生—妇产科学]