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作 者:郑冬妮[1] 张梨 周杨 ZHENG Dongni;ZHANG Li;ZHOU Yang(The Fifth People′s Hospital of Chengdu,Chengdu,Sichuan,China 611130)
机构地区:[1]四川省成都市第五人民医院,四川成都611130
出 处:《中国药业》2023年第20期30-33,共4页China Pharmaceuticals
基 金:四川省成都市医学科研课题[2022435;2021097]。
摘 要:目的促进卡泊芬净和米卡芬净的临床合理应用。方法参考卡泊芬净和米卡芬净药品说明书及相关指南,建立合理利用评价标准。采用加权TOPSIS法评价医院2013年至2021年使用此两药病例的用药合理性,分析其临床用药存在的问题。结果219个病例中,相对接近度小于60%的有59个(26.94%),其中米卡芬净50个(84.75%),卡泊芬净9个(15.25%)。卡泊芬净临床使用主要存在用药指征不足、医师权限管理及病程记录不完善等问题;米卡芬净临床使用的主要问题为病程记录不完整。结论卡泊芬净的用药指征不足、医师权限管理是临床关注的重点问题,卡泊芬净和米卡芬净的病程记录书写及病原学的筛查也是需要加强管理的重点环节。Objective To promote the clinical rational application of caspofungin and micafungin.Methods Based on the drug instructions and related guidelines,an evaluation criterion of rational use of caspofungin and micafungin was established.The weighted TOPSIS method was used to evaluate the rationality of the cases using the above two drugs in a hospital from 2013 to 2021,and the problems in the clinical medication were analyzed.Results Among the 219 cases,there were 59 cases(26.94%)with a relative approach degree of medication rationality lower than 60%,including 50 cases of micafungin(84.75%)and nine cases of caspofungin(15.25%).The main problems in the clinical use of caspofungin were insufficient medication indications,incomplete physician authority management,incomplete disease course records,and the main problem in the clinical use of micafungin was incomplete disease course records.Conclusion Insufficient medication indications and physician authority management in the application of caspofungin are the clinical concerns,the writing of disease course records and pathogen screening of caspofungin and micafungin also need to be strengthened in management.
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