Catalyst-free ultrasound assisted novel one pot pseudo five component synthesis of aryl-bis-[1H-pyrazol-5-ol-4-yl]methanes,het(aryl)-bis-[1H-pyrazol-5-ol-4-yl]methanes and their 1-phenyl derivatives in aqueous medium  

作　　者：Sudha S Mohamed Afzal Pasha 

机构地区：[1]Department of Chemistry and Biochemistry,Jyoti Nivas College Autonomous,Bengaluru 560095,India [2]Department of Studies in Chemistry,Jnanabharathi Campus,Bangalore University,Bengaluru 560056,India

出　　处：《Green Synthesis and Catalysis》2022年第2期190-193,共4页绿色合成与催化（英文）

基　　金：Dr.Mohamed Afzal Pasha acknowledges the University Grants Commission(UGC),New Delhi,INDIA for the BSR Faculty Fellowship(No.F.18–1/2011(BSR),November 2019).

摘　　要：An efficient,catalyst-free and eco-friendly ultrasound-assisted novel one-pot pseudo-five-component synthesis of aryl-bis-[1H-pyrazol-5-ol-4yl]methanes,het(aryl)-bis-[1H-pyrazol-5-ol-4yl]methanes and their 1-phenyl derivatives in water is reported.The products were obtained in excellent yield in shorter duration with high purity,by simple filtration.This synthetic methodology has been optimized and discussed herein.

关 键 词：Bis pyrozolyl-methanes Ethyl acetoacetate Aromatic/het(aryl)aldehydes Hydrazine/phenyl hydrazine One-pot multi-component synthesis Ultrasound 

分 类 号：O62[理学—有机化学]