Palladacyclic N-heterocyclic carbene precatalysts for transition metal catalysis  

作　　者：Kun Wang Ruoqian Fan Xian Wei Weiwei Fang 

机构地区：[1]Jiangsu Co-Innovation Center of Efficient Processing and Utilization of Forest Resources,International Innovation Center for Forest Chemicals and Materials,College of Chemical Engineering,Nanjing Forestry University,Nanjing 210037,China

出　　处：《Green Synthesis and Catalysis》2022年第4期327-338,共12页绿色合成与催化（英文）

基　　金：Financial support from the National Natural Science Foundation of China(No.22101133);the Natural Science Foundation of Jiangsu Province(No.BK20200768)is greatly acknowledged.

摘　　要：Palladacycles remain a challenging and significant research field in organic chemistry and have emerged as a type of powerful and versatile precatalysts or key active intermediates for transition metal catalysis.These achievements in this area are correlated to the design and development of useful ancillary ligands,such as N-heterocyclic carbenes(NHCs),which not only stabilize the actual catalytic active species facilitating the transformations,but also provide additional control over the selectivity of reactions.In this context,NHCs-ligated palladacycles(NHCP_(dcycles))with different electronic and steric properties have been synthesized and applied as green precatalysts(high stability and activity,low catalyst loading and mild reaction conditions)to accelerate transition metalcatalyzed reactions.Therefore,this review focuses mainly on the strategy of NHC-Pd_(cycles) design and catalytic results obtained from representative transition metal catalysis,such as Suzuki-Miyaura,Heck-Mizoroki and Sonogashira cross-coupling reactions,Buchwald-Hartwig amination,carbonylation as well as arylation.At last,the current limitations and potential trends for further development of NHC-Pdcycles are also highlighted.

关 键 词：N-Heterocyclic carbene PALLADACYCLE Precatalyst Cross-coupling reaction Transition metal catalysis 

分 类 号：O64[理学—物理化学]