Tunable synthesis of furfurylamines orβ-amino alcohols via Ru-catalyzed N–H functionalization using biomass-derived polyols  

作　　者：Le Jia Xue Wang Xiaolong Gao Mohamed Makha Xi-Cun Wang Yuehui Li 

机构地区：[1]State Key Laboratory for Oxo Synthesis and Selective Oxidation,Suzhou Research Institute of LICP,Lanzhou Institute of Chemical Physics(LICP),Chinese Academy of Sciences,Lanzhou 730000,China [2]College of Chemistry and Chemical Engineering,Northwest Normal University,Lanzhou 730070,China

出　　处：《Green Synthesis and Catalysis》2022年第3期259-264,共6页绿色合成与催化（英文）

基　　金：support from the National Natural Science Foundation of China(NSFC,Nos.21633013,22022204).

摘　　要：We report the highly efficient conversion of readily available biomass-derived polyols with amines to valuable furfurylamines orβ-amino alcohols compounds using ruthenium catalysis.The reaction outcome is readily tuned by the simple addition of 4Åmolecular sieves(furfurylamines vs.β-amino alcohols)with high chemo-selectivity.The proposed reaction mechanism involves ruthenium-catalyzed hydrogen borrowing for the reduction of the imine intermediate and C–C bond cleavage of polyols via a retro-aldol process.A series of arylamines was suc-cessfully transformed into the desired products with moderate to good yields.

关 键 词：POLYOLS Furfurylamines β-Amino alcohols Ru-catalyzed 

分 类 号：O62[理学—有机化学]