Hunger extends lifespan by modulating histone proteins  

作　　者：Hailan Liu Hongjie Li Yong Xu 

机构地区：[1]USDA/ARS Children’s Nutrition Research Center,Department of Pediatrics,Baylor College of Medicine,Houston,TX 77030,United States [2]Department of Molecular and Human Genetics,Baylor College of Medicine,Houston,TX 77030,United States [3]Huffington Center on Aging,Baylor College of Medicine,Houston,TX 77030,United States [4]Department of Molecular and Cellular Biology,Baylor College of Medicine,Houston,TX 77030,United States [5]Section of Endocrinology,Diabetes,and Metabolism,Department of Medicine,Baylor College of Medicine,Houston,TX 77030,United States

出　　处：《Life Metabolism》2023年第4期3-4,共2页生命（代谢（英文）

摘　　要：In a recent study published in Science,Weaver et al.provided insights into the effects of hunger on longevity.Inducing a state of hunger,either through restricting isoleucine intake or by stimulating R50H05 hunger neurons,resulted in an extension of lifespan in fruit flies.This effect is mediated by the modula-tion of histone proteins in the brain.

关 键 词：modul restrict INSIGHT 

分 类 号：Q51[生物学—生物化学]