平衡针联合骨折挫伤胶囊治疗急性踝关节扭伤临床观察  

Clinical Observation of Balance Needle Combined with Guzhe Cuoshang Capsules in the Treatment of Acute Ankle Sprain

作　　者：刘广宇[1] 徐西林[1] 李志刚[1] 王春龙[1] Liu Guangyu;Xu Xilin;Li Zhigang;Wang Chunlong(The Second Affiliated Hospital of Heilongjiang University of Traditional Chinese Medicine,Heilongjiang,Harbin 150001,China)

机构地区：[1]黑龙江中医药大学附属第二医院,黑龙江哈尔滨150001

出　　处：《中国中医急症》2023年第10期1774-1778,共5页Journal of Emergency in Traditional Chinese Medicine

基　　金：黑龙江省中医药学会青年中医药科技创新计划项目(ZHY2023-190)。

摘　　要：目的 观察平衡针联合骨折挫伤胶囊治疗急性踝关节扭伤的临床疗效及其对损伤韧带形态学的影响。方法 将114例急性踝关节扭伤患者采用随机数字表法分为对照组与观察组各57例。对照组给予西医常规干预措施,观察组加予平衡针和骨折挫伤胶囊内服。两组疗程均为2周。比较治疗前后疼痛、压痛、肿胀功能受限、美国足与踝关节协会(AOFAS)踝-后足功能评分;比较两组疼痛和肿胀消失时间;检测治疗前后外周肘静脉血肿瘤坏死因子(TNF-α)、白细胞介素-1β(IL-1β)、丙二醛(MDA)、超氧化物歧化酶(SOD)水平;治疗前及治疗后3个月,以超声检查评估损伤韧带的恢复情况,比较患侧和健侧韧带的长度、宽度和厚度差值。比较两组临床总有效率。结果 两组治疗后疼痛、压痛、肿胀和功能受限评分均较治疗前明显下降(P <0.05),且观察组各症状、体征评分均低于对照组(P <0.05);治疗后观察组疼痛和肿胀消失时间短于对照组(P <0.05);两组治疗后AOFAS踝-后足评分均较治疗前升高(P <0.05),且观察组AOFAS踝-后足评分高于对照组(P <0.05);两组治疗后外周血TNF-α、IL-1β、MDA水平较治疗前降低(P <0.05)且观察组低于对照组(P <0.05),SOD水平升高(P <0.05),且观察组高于对照组(P <0.05);治疗后观察组损伤与健侧韧带形态各参数均低于对照组(P <0.05)。观察组临床总有效率为94.74%,高于对照组的82.46%(P <0.05)。结论 平衡针联合骨折挫伤胶囊内服治疗急性踝关节扭伤可缩短病程,能减轻氧化应激和炎症反应,改善损伤韧带形态,有助于踝关节形态和功能的恢复,临床疗效优于西医常规综合治疗措施。Objective:To evaluate the clinical effect of balance needle combined with Guzhe Cuoshang Capsules in the treatment of acute ankle sprain and its influence on the morphology of injured ligament.Methods:A total of 114 patients with acute ankle sprain were randomly divided into the control group and observation group,57 cas⁃es in each group.The control group was given routine intervention measures of western medicine,including com⁃prehensive measures such as rest,ice compress,pressure bandage,raising the affected limb,anti-inflammatory and analgesic,functional exercise,etc.The observation group was given balance needle and Guzhe Cuoshang Capsules.The course of treatment was two weeks.The pain,tenderness,swelling function limitation and AOFAS ankle-poste⁃rior foot function score before and after treatment were compared;the disappearance time of pain and swelling was compared between the two groups;the tumor necrosis factor(TNF-α)in peripheral elbow vein blood,interleukin 1β(IL-1β),malondialdehyde(MDA)and superoxide dismutase(SOD)levels were detected;before and 3 months after treatment,the recovery of the injured ligament was evaluated by ultrasound,and the difference in length,width and thickness between the affected side and the healthy side was compared.The total clinical effective rate of the two groups was compared.Results:After treatment,the scores of pain,tenderness,swelling and functional limitation in the two groups were significantly lower than those before treatment(P<0.05),and the scores of symp⁃toms and signs in the observation group were lower than those in the control group(P<0.05);after treatment,the disappearance time of pain and swelling in the observation group was shorter than that in the control group(P<0.05);after treatment,the AOFAS ankle-hindfoot score of the two groups was higher than that before treatment(P<0.05),and the AOFAS ankle-hindfoot score of the observation group was higher than that of the control group(P<0.05);after treatment,the peripheral blood TNF-α,IL-1β,MDA was lo

关 键 词：急性踝关节扭伤 平衡针 骨折挫伤胶囊 韧带形态 炎症因子 氧化应激 

分 类 号：R684.7[医药卫生—骨科学]