International study of the Complex Stress Reaction Syndrome:Implications for transdiagnostic clinical practice  

作　　者：Sari Goldstein Ferber Aron Weller Adele M Hayes Tracy D Vannorsdall Yaroup Ajlouni Mo'nes Qudah Gil Zalsman Gal Shoval Tommaso Benedetto Jannini Racquel Fiedler Lily X Chen Danielle R Shayani Elin Kachuki Dory Dana Stolowicz-Melman Connor Evans Megan Trow Giorgio Di Lorenzo Rodolfo Rossi 

机构地区：[1]Department of Psychological and Brain Sciences,University of Delaware,Newark,DE 19716,United States [2]Department of Psychology,Bar Ilan University,Ramat Gan 5290002,Israel [3]Department of Psychology and The Gonda Brain Research Center,Bar Ilan University,Ramat Gan 5290002,Israel [4]Department of Psychiatry and Behavioral Sciences,Department of Neurology,The Johns Hopkins University School of Medicine,Baltimore,MD 21287,United States [5]Jordan Health Aid-International,Amman 1234,Jordan [6]Geha Mental Health Center,Petah Tiqva,Israel and Faculty of Medicine,Tel Aviv University,Ramat Aviv 6997801,Israel [7]Division of Molecular Imaging and Neuropathology,Department of Psychiatry,Columbia University,New York,NY 10032,United States [8]Department of Neuroscience,Princeton University,Princeton,NJ 08544,United States [9]Department of Systems Medicine,Tor Vergata University of Rome,Rome 00133,Italy [10]UNSW School of Psychology,UNSW Sydney,Sydney 2052,Australia [11]Department of Biology,Pacific University,Forest Grove,OR 97116,United States [12]Oregon Chapter of Fulbright Association,Oregon,OR 97045,United States [13]Department of Systems Medicine,Tor Vergata University of Rome,Rome 00179,Italy [14]IRCCS,Fondazione Santa Lucia,Rome 00179,Italy

出　　处：《World Journal of Psychiatry》2023年第10期803-815,共13页世界精神病学杂志

摘　　要：BACKGROUND The debate regarding diagnostic classification systems in psychiatry(categorial vs dimensional systems)has essential implications for the diagnosis,prevention and treatment of stress reactions.We previously found a unique pattern of stress reaction in a study executed during the coronavirus disease 2019 pandemic using large representative samples in two countries,and termed it the Complex Stress Reaction Syndrome(CSRS).AIM To investigate CSRS,Type A(psychiatric symptoms,spanning anxiety,depression,stress symptoms,and posttraumatic stress disorder(PTSD)),with or without long-coronavirus disease(COVID)residuals(CSRS,Type B,neuropsychiatric symptoms spanning cognitive deficits and fatigue,excluding systemic symptoms).Our two-tailed hypothesis was that CSRS is a condition related to an unrecognized type of stress reaction in daily life in the general population(Type A)or that it is related to the severe acute respiratory syndrome coronavirus 2 infection and its long-COVID residuals(Type B).METHODS 977 individuals in four continents(North America,Europe,Australia and the Middle East)completed the online study questionnaire in six languages using the Qualtrics platform.The study was managed by six teams in six countries that promoted the study on social media.The questionnaire assessed anxiety,depression,stress symptoms and PTSD(CSRS,Type A),cognitive deficits and fatigue(CSRS,Type B).The data were analyzed using Proportion Analyses,Multivariate Analysis of Co-Variance(MANCOVA),linear regression analyses and validated clinical cutoff points.RESULTS The results of the Proportion Analyses showed that the prevalence of 4 symptoms spanning anxiety,depression,stress symptoms,and PTSD was significantly higher than the most prevalent combinations of fewer symptoms across 4 continents,age groups,and gender.This supports the transdiagnostic argument embedded in the CSRS(Type A).The same pattern of results was found in infected/recovered individuals.The prevalence of the 4 psychiatric symptoms combination was signific

关 键 词：TRANSDIAGNOSTIC Complex Stress Reaction Syndrome Stress reactivity Affective disorders Debate in psychiatry 

分 类 号：R563.1[医药卫生—呼吸系统]