Candida endocarditis: Update on management considerations  

作　　者：Yasser Jamil Akintayo Akinleye Mojtaba Mirzaei Matthew Lempel Kassem Farhat Samuel Pan 

机构地区：[1]Department of Internal Medicine,Yale School of Medicine,Waterbury,CT 06708,United States [2]Department of Rheumatology,Yale School of Medicine,New Haven,CT 06510,United States [3]Department of Infectious Disease,Yale School of Medicine,Waterbury,CT 06708,United States

出　　处：《World Journal of Cardiology》2023年第10期469-478,共10页世界心脏病学杂志（英文版）（电子版）

摘　　要：The rise in incidence rates of invasive candidiasis warrants an increase in atten-tion and efforts toward preventing and treating this virulent infection.Cardiac involvement is one of the most feared sequelae and has a poor prognosis.Despite the introduction of several novel antifungal agents over the past quarter century,complications and mortality rates due to Candida endocarditis have remained high.Although fungal endocarditis has a mechanism similar to bacterial endocar-ditis,no specific diagnostic criteria or algorithm exists to help guide its manage-ment.Furthermore,recent data has questioned the current guidelines recommen-ding a combined approach of antifungal agents with surgical valve or indwelling prostheses removal.With the emergence of multidrug-resistant Candida auris,a focus on improved prophylactic measures and management strategies is nece-ssary.

关 键 词：CANDIDA Candida endocarditis Fungal endocarditis Invasive fungal infection 

分 类 号：R542.41[医药卫生—心血管疾病]